Chlormephos

  • Chlormethylfos
  • S-(Chloromethy) O,O-diethyl phosphorodithioate
  • S-Chloromethyl O,O-diethyl phosphorodithioate
  • Phosphorodithioic acid, S-(chloromethyl) O,O-diethyl ester
Formula
C5H12ClO2PS2
Structure
Description
Colorless liquid.
Uses
Non-systemic insecticide with contact and some stomach action.

Registry Numbers and Inventories.
CAS
24934-91-6
EC (EINECS/ELINCS)
246-538-1
EC Index Number
015-114-00-6
EC Class
Very toxic
RTECS
TD5170000
RTECS class
Agricultural Chemical and Pesticide
Beilstein/Gmelin
1680996
Beilstein Reference
4-01-00-03088
EPA OPP
295300
Swiss Giftliste 1
G-9813

Properties.
Formula
C5H12ClO2PS2
Formula mass
234.71
Boiling point, °C
93 - 95 (1 torr)
Vapor pressure, mmHg
0.0056
Density
1.26 g/cm3 (20 C)
Solubility in water
60 mg/L @ 20 C
Refractive index
1.52 (20 C)

Hazards and Protection.
Storage
Rooms used for storage only should be soundly constructed and fitted with secure locks. Floors should be kept clear and pesticides clearly identified if repacking is carried out in storage rooms, adequate light should be available; floors should be impervious and sound. Pesticides pesticides containers must be provided with labels indicating the degree of toxicity of the product they contain. The labels must not only give a short description of how to use the prepn, but also state basic precautions to be taken when applying it. Organophosphorus pesticides pesticides of any degree of toxicity should be transported in containers which are clearly labelled, leak-proof, and not easily damaged. They should never be transported or stored beside, or above any type of food, and all spillages should be immediately reported.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Workers handling and applying organophosphate pesticides must be given personal protective equipment comprising overalls made of a tight fabric or polyvinyl chloride, gloves, and rubber boots. The eyes should be protected by goggles.
Respirators
Respiratory protection (supplied-air respirator with full facepiece or self-contained breathing apparatus) should be available where these compounds are manufactured or used and should be worn in case of emergency and overexposure.<BR>Must wear a respirator with an activated-carbon gas filter cartridge affording protection for a determined number of working hours.
Small spills/leaks
(Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Remove and isolate contaminated clothing at the site. Do not touch spilled material. Use water spray to reduce vapors. Take up small spills with sand or other noncombustible absorbent material and place in containers for later disposal. Dike far ahead of large spills for later disposal.
Stability
Stable in neutral and weakly acidic media at room temperature, but hydrolyzed by dilute acids and alkalis at 30 C. Rapidly hydrolyzed in alkaline media.

Fire.
Fire fighting
(Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Stay upwind; keep out of low areas. Move container from fire area if you can do it without risk. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material. Wear positive pressure breathing apparatus and special protective clothing.(Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) This material may burn, but does not ignite readily. For small fires, use dry chemical, carbon dioxide, water spray, or foam. For large fires, use water spray, fog, or foam.

Health.
Poison_Class
2
Exposure effects
Fever, low heart rate and abnormally low blood pressure, or rapid heart rate and elevated blood pressure may occur. Headache, dizziness, muscle spasms and profound weakness are common. Alterations of level of consciousness, anxiety, paralysis, seizures and coma may occur. Seizures may be more common in children.
   Ingestion
Vomiting, hypersalivation, diarrhea, fecal incontinence and abdominal pain may occur.
   Inhalation
Dyspnea, rales, bronchorrhea, bronchospasm, or tachypnea may be noted. Noncardiogenic pulmonary edema may occur in severe cases. Chemical pneumonitis may be seen.
   Skin
Sweating is a consistent but not universal sign.
   Eyes
Constriction of the pupil, tearing, and blurred vision are common. Prolonged dialation of the pupils may occur in severe poisonings. Opsoclonus has been reported in one case. Salivation commonly occurs.

First aid
 
   Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Systemic effects can occur from dermal exposure to organophosphates. Remove contaminated clothing, wash skin, hair and nails vigorously with repeated soap washings. Leather absorbs pesticides; all contaminated leather should be discarded. Rescue personnel and bystanders should avoid direct contact with contaminated skin, clothing, or other objects.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Patients symptomatic following exposure should be observed in a controlled setting until all signs and symptoms have fully resolved. Suction oral secretions until atropinization. Treatment should include recommendations listed in the oral exposure section when appropriate. Contraindications - succinylcholine and other cholinergic agents are contraindicated. Note: see treatment of eye exposure in main body of this document for complete information.

Transport.
USCG CHRIS Code
CRM