Chloroacetone

  • Monochloroacetone
  • 1-Chloro-2-propanone
  • Acetonyl chloride
Formula
ClCH2COCH3
Structure
Description
Colorless liquid, pungent, irritating odor, lachrymator.
Uses
Manufacture of couplers for color photography, as enzyme inactivator, intermediary in manufacture of perfumes, antioxidants, drugs, in insecticide formulations, in photopolymerization of vinyl compounds, proposed as catalyst in tetraethyllead production, as selective solvent for separating diolefins, proposed as tear gas for military and police use.

Registry Numbers and Inventories.
CAS
78-95-5
EC (EINECS/ELINCS)
201-161-1
EC Class
flammable, toxic, irritant, dangerous for the environment
R 10 23/24/25 36/37/38 50
S 16 26 36/37/39 45
RTECS
UC0700000
RTECS class
Mutagen; Human Data
UN (DOT)
1695
Merck
13,2131
Beilstein/Gmelin
605369
Beilstein Reference
4-01-00-03215
Swiss Giftliste 1
G-1380
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C3H5ClO
Formula mass
92.53
Melting point, °C
-44
Boiling point, °C
120
Vapor pressure, mmHg
15 (25 C)
Vapor density (air=1)
3.19
Saturation Concentration
1.45 x 10(4) ppm (1.45%) at 25 dec C (calculated); 2.76 x 10(4) ppm (2.76%) at 20 C (calculated)
Density
1.126 g/cm3 (25 C)
Solubility in water
Soluble
Viscosity
1.11 mPas 25 C
Surface tension
35.27 g/s2 (20 C)
Refractive index
1.4338 (20 C)
Partition coefficient, pKow
0.43
Heat of vaporization
35.8 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator/flammables.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Use only in a chemical fume hood. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors. Water spray may reduce vapor but may not prevent ignition in closed spaces.
Disposal code
2
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong acids, strong bases, strong oxidizing agents, strong reducing agents.
Decomposition
Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
28
Autoignition, °C
610
Lower exp. limit, %
3.4
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Containers may explode when heated. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
Fire potential
HIGHLY FLAMMABLE.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion and poison hazard indoors, outdoors or in sewers. May polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
2
 
 
Reactivity
0
 

Health.
Poison_Class
1
Exposure effects
Effects may be delayed.
   Ingestion
Harmful if swallowed. May cause severe and permanent damage to the digestive tract. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage. May cause perforation of the digestive tract. Ingestion of large amounts may cause CNS depression. May cause spleen damage. May cause systemic effects.
   Inhalation
May be fatal if inhaled. Causes chemical burns to the respiratory tract. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. May cause systemic effects. Vapors are extremely irritating to the respiratory tract. May cause burning sensation in the chest.
   Skin
May be fatal if absorbed through the skin. Causes skin burns. May cause cyanosis of the extremities. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
   Eyes
Causes eye burns. Lachrymator. May cause chemical conjunctivitis and corneal damage.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Discard contaminated clothing in a manner which limits further exposure.
   Eyes
Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
1695
Response guide
Hazard class
6.1 (Forbidden for unstabilized)
PRTC
T
Packing Group
I
 
HS Code
2914 70 90
 
Std. Transport #
4921558