Chloroacetonitrile

  • Chloromethyl cyanide
  • 2-Chloroacetonitrile
  • Chlorocyanomethane
Formula
ClCH2CN
Structure
Description
A colorless to pale yellow liquid with a pungent odor.
Uses
Chloroacetonitrile's major uses as are an organic intermediate in the manufacture of the insecticide fenoxycarb and the cardiovascular drug guanethidine.

Registry Numbers and Inventories.
CAS
107-14-2
EC (EINECS/ELINCS)
203-467-0
EC Index Number
608-008-00-1
EC Class
Toxic; Dangerous for the Environment
R 23/24/25 51/53
RTECS
AL8225000
RTECS class
Tumorigen; Mutagen; Primary Irritant
UN (DOT)
2668
Beilstein/Gmelin
506028
Beilstein Reference
4-02-00-00492
RCRA
D003
Swiss Giftliste 1
G-2180
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C2H2ClN
Formula mass
75.50
Melting point, °C
-66
Boiling point, °C
125
Vapor pressure, mmHg
11.5
Vapor density (air=1)
2.6
Critical temperature
352
Critical pressure
46
Density
1.204 g/cm3 (11 C)
Solubility in water
Insoluble
Refractive index
1.493 (25 C)
Partition coefficient, pKow
0.45

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
D1A D2B
Handling
Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Disposal code
9
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong reducing agents, strong oxidizing agents, strong bases, strong acids.
Decomposition
Hydrogen chloride, hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
54
Lower exp. limit, %
1
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
Fire potential
HIGHLY FLAMMABLE.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion and poison hazard indoors, outdoors or in sewers. May polymerize explosively when heated or involved in a fire.
Combustion products
When heated to decomposition it emits very toxic fumes of cl-, nox, and cn- chlorides, nitrogen oxides, and cyanides.
Health
3
 
Flammability
2
 
 
Reactivity
0
 

Health.
Poison_Class
2
Exposure effects
Chronic exposure may cause degenerative lesions of the heart, liver, and kidneys. Chronic inhalation may cause damage to the respiratory tract and bronchi which may result in dealth.
   Ingestion
Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause headache.
   Inhalation
May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. May cause drowsiness, unconsciousness, and central nervous system depression. Vapors may cause dizziness or suffocation. Harmful if inhaled.
   Skin
Causes mild skin irritation. May be fatal if absorbed through the skin. Causes redness and pain. Substance is readily absorbed through the skin.
   Eyes
Causes moderate eye irritation. Causes redness and pain. Lachrymator.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Wash mouth out with water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2668
Response guide
Hazard class
6.1
PRTC
T
Packing Group
II
 
HS Code
2926 90 95
 
Std. Transport #
4921009