Chloroacetyl chloride

  • Chloroacetic Acid Chloride;
  • Monochloroacetyl Chloride
Formula
ClCH2COCl
Structure
Description
Colorless to yellowish liquid, very pungent odor.
Uses
Tear gas, intermediate, used to prepare chloracetophenone.

Registry Numbers and Inventories.
CAS
79-04-9
EC (EINECS/ELINCS)
201-171-6
EC Index Number
607-080-00-1
EC Class
Reacts violently with water; Contact with water liberates toxic gas; Toxic; Corrosive; Dangerous for the Environment
R 14 23/24/25 35 48/23 50
S 7/8 9 26 36/37/39 45 61
RTECS
AO6475000
RTECS class
Other
UN (DOT)
1752
Merck
13,2074
Beilstein/Gmelin
605439
Beilstein Reference
4-02-00-00488
Swiss Giftliste 1
G-1382
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C2H2Cl2O
Formula mass
112.94
Melting point, °C
-22.5
Boiling point, °C
105
Vapor pressure, mmHg
29 (25 C)
Vapor density (air=1)
3.9
Saturation Concentration
25004 ppm (2.5%) (calculated)
Odor Threshold Odor threshold 0.023 ppm
Critical temperature
308
Critical pressure
50.4
Density
1.426 g/cm3 (20 C)
Solubility in water
Decomposes
Viscosity
4.51x10-2 n/m @ 251.15 K
Refractive index
1.4541 (20 C)
Partition coefficient, pKow
0.98
Heat of fusion
0.5 kJ/mol
Heat of vaporization
41.2 kJ/mol
Heat of combustion
-1039 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Do not store near alkaline substances. Store protected from moisture.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Wash clothing before reuse. Discard contaminated shoes.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Do not expose spill to water.
Disposal code
11
Stability
Decomposes when heated.
Incompatibilities
Alcohols, oxidizing agents, and strong bases
Decomposition
Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
34
Autoignition, °C
> 500
Upper exp. limit, %
16.3
Fire fighting
Use dry chemical or carbon dioxide. Do not use water on material itself. If large quantities of combustibles are involved, use water in flooding quantities as spray and fog. Use water spray to knock-down vapors. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible.
Fire potential
Not combustible, but if involved in a fire decomposes to produce hydrogen chloride.
Hazards
Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas.
Combustion products
Heat of fire can cause decomposition, with evolution of highly toxic and irritating hydrogen chloride and phosgene vapors.
Health
3
 
Flammability
0
 
 
Reactivity
1
 

Health.
Exposure limit(s)
TLV: 0.05 ppm; 0.23 mg/m3 (skin) (ACGIH 1997). TLV (as STEL): 0.15 ppm; 0.69 mg/m3 (ACGIH 1997). NIOSH REL: TWA 0.05 ppm (0.2 mg/m3)
Poison_Class
2
Exposure effects
Agitation and syncope, both attributed to panic, have been reported.
   Ingestion
Harmful if swallowed. Causes gastrointestinal tract burns.
   Inhalation
Harmful if inhaled. Causes severe irritation of upper respiratory tract with coughing, burns, breathing difficulty, and possible coma. May cause abdominal pain, nausea, vomiting, and inflammation of the gums and mouth.
   Skin
Harmful if absorbed through the skin. Causes severe skin irritation and burns.
   Eyes
Lachrymator. Causes eye irritation and burns.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen.
   Skin
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
Get medical aid immediately. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
1752
Response guide
Hazard class
6.1
PRTC
T
Packing Group
I
 
USCG CHRIS Code
CAC
 
HS Code
2915 90 80
 
Std. Transport #
4923117 4931210