- Chloroacetic Acid Chloride;
- Monochloroacetyl Chloride
Colorless to yellowish liquid, very pungent odor.
Tear gas, intermediate, used to prepare chloracetophenone.
Registry Numbers and Inventories.
EC Index Number
Reacts violently with water; Contact with water liberates toxic gas; Toxic; Corrosive; Dangerous for the Environment
R 14 23/24/25 35 48/23 50
S 7/8 9 26 36/37/39 45 61
Swiss Giftliste 1
Japan ENCS (MITI)
Melting point, °C
Boiling point, °C
Vapor pressure, mmHg
29 (25 C)
Vapor density (air=1)
25004 ppm (2.5%) (calculated)
Odor Threshold Odor threshold 0.023 ppm
1.426 g/cm3 (20 C)
Solubility in water
4.51x10-2 n/m @ 251.15 K
1.4541 (20 C)
Partition coefficient, pKow
Heat of fusion
Heat of vaporization
Heat of combustion
Hazards and Protection.
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Do not store near alkaline substances. Store protected from moisture.
Wash thoroughly after handling. Use only in a well ventilated area. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Wash clothing before reuse. Discard contaminated shoes.
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Do not expose spill to water.
Decomposes when heated.
Alcohols, oxidizing agents, and strong bases
Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide.
Upper exp. limit, %
Use dry chemical or carbon dioxide. Do not use water on material itself. If large quantities of combustibles are involved, use water in flooding quantities as spray and fog. Use water spray to knock-down vapors. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible.
Not combustible, but if involved in a fire decomposes to produce hydrogen chloride.
Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas.
Heat of fire can cause decomposition, with evolution of highly toxic and irritating hydrogen chloride and phosgene vapors.
TLV: 0.05 ppm; 0.23 mg/m3 (skin) (ACGIH 1997). TLV (as STEL): 0.15 ppm; 0.69 mg/m3 (ACGIH 1997). NIOSH REL: TWA 0.05 ppm (0.2 mg/m3)
Agitation and syncope, both attributed to panic, have been reported.
Harmful if swallowed. Causes gastrointestinal tract burns.
Harmful if inhaled. Causes severe irritation of upper respiratory tract with coughing, burns, breathing difficulty, and possible coma. May cause abdominal pain, nausea, vomiting, and inflammation of the gums and mouth.
Harmful if absorbed through the skin. Causes severe skin irritation and burns.
Lachrymator. Causes eye irritation and burns.
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen.
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Get medical aid immediately. Extensive irrigation is required (at least 30 minutes).
USCG CHRIS Code
2915 90 80
Std. Transport #