Chlorodifluoromethane

  • Refrigerant gas R-22
  • Freon 22
  • Monochlorodifluoromethane
  • Difluorochloromethane
Formula
CHClF2
Structure
Description
Chlorodifluoromethane is a colorless gas with an ethereal odor.
Uses
Propellant, Fumigant, Insecticide

Registry Numbers and Inventories.
CAS
75-45-6
EC (EINECS/ELINCS)
200-871-9
RTECS
PA6390000
RTECS class
Tumorigen; Mutagen; Reproductive Effector
UN (DOT)
1018
Beilstein/Gmelin
1731036
Beilstein Reference
4-01-00-00032
EPA OPP
15
Swiss Giftliste 1
G-2010
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
CHClF2
Formula mass
86.47
Melting point, °C
-157.4
Boiling point, °C
-40.8
Vapor pressure, mmHg
6290 (25 C)
Vapor density (air=1)
2.98
Critical temperature
96
Critical pressure
49.25
Density
1.41 g/cm3 (20 C)
Solubility in water
3 g/L
Viscosity
0.00328 g/(cm s) (-33 C)
Surface tension
1.25 g/s2 (80 C)
Refractive index
1.264 (22 C)
Dipole moment
1.43 D (22 C)
Dielectric constant
6.0 22 C)
Partition coefficient, pKow
1.08
Thermal expansion
0.0035/K at 15 C
Heat of fusion
4.1 kJ/mol
Heat of vaporization
20.8 kJ/mol

Hazards and Protection.
Storage
Keep container tightly closed. Keep away from heat, sparks and flames.
A
Handling
Containers of this material may be hazardous when emptied. Since emptied containers retain product residues (vapor, liquid, and/or solid), all hazard precautions given in the data sheet must be observed.
Protection
Wear appropriate clothing to prevent any reasonable probability of skin contact. Wear eye protection to prevent any possibility of eye contact.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Attempt to stop leak if without undue personnel hazard.
Stability
Stable at normal temperatures and pressure.
Incompatibilities
Incompatible with alkalis, alkaline earth metals (e.g., powdered aluminum, sodium, potassium, zinc).
Decomposition
Decomposition gases are toxic and irritating. When heated to decomp. They evolve highly toxic. Fumes of hydrogen chloride and hydrogen fluoride. All fluorocarbons will undergo thermal decomposition when exposed to flame or red-hot metal. Decomposition products of the chlorofluorocarbons will include hydrofluoric and hydrochloric acid along with smaller amounts of phosgene and carbonyl fluoride. The last compound is very unstable to hydrolysis and quickly changes to hydrofluoric acid and carbon dioxide in the presence of moisture.

Fire.
Flash Point,°C
-78
Autoignition, °C
632
Upper exp. limit, %
26.9
Fire fighting
Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible.
Fire potential
Slightly flammable.
Hazards
Vapors from liquefied gas are initially heavier than air and spread along ground.
Combustion products
Decomposition gases are toxic and irritating.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV (as TWA): 1000 ppm; 3540 mg/m3 (ACGIH 1992-1993). MAK: 500 ppm; 1800 mg/m3; IV, C (1992). NIOSH REL: TWA 1000 ppm (3500 mg/m3) ST 1250 ppm (4375 mg/m3)
Poison_Class
5
Exposure effects
Headache, dizziness, and disorientation are common. Cerebral edema may be found on autopsy. Dichlorodifluoromethane was not teratogenic in rats and rabbits. <br>The reproductive effects of 1,1,1,2-tetrafluoroethane were studied in rats. No adverse effects on reproductive performance was noted or on the development, maturation or reproductive performance of up to two successive generations.
   Ingestion
Nausea may develop. Ingestion of a small amount of trichlorofluoromethane resulted in necrosis and perforation of the stomach in one patient.
   Inhalation
Pulmonary irritation, bronchial constriction, cough, dyspnea, and chest tightness may develop after inhalation. Chronic pulmonary hyperreactivity may occur. Adult respiratory distress syndrome has been reported following acute inhalational exposures. Pulmonary edema is an autopsy finding in fatal cases.
   Skin
Dermal contact may result in defatting, irritation or contact dermatitis. Severe frostbite has been reported as an effect of freon exposure. Injection causes transient pain, erythema and edema.
   Eyes
EYES - Eye irritation occurs with ambient exposure. Frostbite of the lids may be severe. NOSE - Nasal irritation occurs with ambient exposure. THROAT - Irritation occurs. Frostbite of the lips, tongue, buccal mucosa and hard palate developed in a man after deliberate inhalation.

First aid
 
   Ingestion
These substances may cause frostbite to the upper airway and gastrointestinal tract after ingestion. Administer oxygen and manage airway as clinically indicated. Emesis, activated charcoal, and gastric lavage are not recommended.
   Inhalation
Provide a quiet calm atmosphere to prevent adrenaline surge if the patient is seen before the onset of cardiac arrhythmias. Minimize physical exertion.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. If frostbite has occurred, refer to dermal treatment in the main body of this document for rewarming.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Ophthamologic consultation should be obtained in any symptomatic patients.

Transport.
UN number
1018
Response guide
Hazard class
2.2
USCG CHRIS Code
MCF
 
36 Halogenated hydrocarbons
Std. Transport #
4904552 4904520