Chlorohydroquinone

  • 2-Chlorohydroquinone
  • Chloroquinol
Formula
C6H5ClO2
Structure
Description
White to light-tan fine crystals.
Uses
Photographic developer, organic intermediate, in dyestuffs, bactericide.

Registry Numbers and Inventories.
CAS
615-67-8
EC (EINECS/ELINCS)
210-442-8
RTECS
MX4800000
RTECS class
Reproductive Effector
Beilstein/Gmelin
636835
Beilstein Reference
4-06-00-05767
Canada DSL/NDSL
DSL
US TSCA
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C6H5ClO2
Formula mass
144.56
Melting point, °C
100
Boiling point, °C
263
Vapor pressure, mmHg
0.0065 (25 C)
Solubility in water
Slightly soluble
pKa/pKb
9.09 (pKa)
Partition coefficient, pKow
1.52
Heat of vaporization
52.1 kJ/mol
Heat of combustion
-2711 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents, strong bases.
Decomposition
Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
120
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Dizziness, headache and delirium have been reported with hydroquinone exposure. Quinone has cause paralysis of the medullary centers and coma. Both quinone and hydroquinone may cause seizures. In rat studies, maternal toxic effects from exposure to hydroquinone included changes in the ovaries, fallopian tubes, and menstrual cycle. Post-implantation mortality was also observed in rat studies. <br>Observed paternal toxic effects from exposure to hydroquinone included changes in the testes, epididymis, sperm duct, prostate, seminal vesicle, Cowper's gland, accessory glands, and male fertility index. <br>Exposure to hydroquinone produced skeletal malformations in chickens and ocular and skeletal malformations in rabbits.
   Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
   Inhalation
Dust is irritating to the respiratory tract. The toxicological properties of this substance have not been fully investigated.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.