Chlorothion

  • o-(3-Chloro-4-nitrophenyl) o,o-dimethyl phosphorothioate
  • Chlorthion
  • Chlorthion methyl
  • Compound 22/190
  • O,O-dimethyl o-(3-Chloro-4-nitrophenyl) phosphorothioate
  • Dimethyl 3-chloro-4-nitrophenyl thionophosphate
Formula
C8H9ClNO5PS
Structure
Description
Pure compound is yellow crystals. Commercial product is a yellow oil.
Uses
This material is used as an insecticide.

Registry Numbers and Inventories.
CAS
500-28-7
EC (EINECS/ELINCS)
207-902-5
EC Index Number
015-042-00-5
EC Class
Harmful
RTECS
TE8050000
RTECS class
Agricultural Chemical and Pesticide
Merck
12,2248
Beilstein/Gmelin
2292513
Beilstein Reference
4-06-00-01357
EPA OPP
34501
Swiss Giftliste 1
G-1426

Properties.
Formula
C8H9ClNO5PS
Formula mass
297.66
Melting point, °C
21
Boiling point, °C
112 (0.04 torr)
Vapor pressure, mmHg
4E-6
Density
1.433 g/cm3 (20 C)
Solubility in water
soluble
Refractive index
1.568 (20 C)
Partition coefficient, pKow
3.45

Hazards and Protection.
Storage
Keep in well ventilated area.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Wear a respirator with an activated-carbon gas filter cartridge affording protection for a determined number of working hours.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
Hydrolyzed by alkali.

Fire.
Fire fighting
Self-contained breathing apparatus, rubber gloves, hats, suits and boots must be worn. Highly toxic fumes are imminent.
Fire potential
Not flammable @ normal temp; thermal decomposition point about 150 C

Health.
Poison_Class
4
Exposure effects
Reduced body temperature or elevated body temperature may occur. Low heart rate and abnormally low blood pressure may develop after moderate to severe poisoning. Rapid heart rate, elevated blood pressure, and changes in respiratory rate may also occur. Early giddiness, anxiety headache, and restlessness followed by ataxia, drowsiness, and confusion are common with moderate to severe exposures. Sporadic reports of human birth defects related to organophosphates have not been fully verified.
   Ingestion
Nausea, vomiting, abdominal cramps, and diarrhea are common muscarinic effects. Both painless and frank clinical pancreatitis have been reported.
   Skin
Profuse sweating is common. Pallor may be noted. Dermal sensitization has been reported.
   Eyes
Constriction of the pupil, tearing, and blurred vision are common. Prolonged dialation of the pupils may occur. Salivation commonly occurs.

First aid
 
   Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.