Chloroxuron

  • C-1933
  • N'-4-(4-Chlorophenoxy)phenyl-N,N-dimethylurea
  • 3-(p-(p-Chlorophenoxy)phenyl)-1,1-dimethylurea
  • 3-(4-(4-Chlorophenoxy)phenyl-1,1-dimethylurea
  • Chloroxifenidim
  • Chlorphencarb
Formula
C15H15ClN2O2
Structure
Description
Odorless colorless powder or white crystals.
Uses
Selective herbicide pre- and post-emergence control of annual broad-leaved weeds and some grasses in peas, beans, carrots, celery, celeriac, onions, leeks, garlic, chives, fennel, parsley, dill, tomatoes, cucurbits, soya beans, strawberries, ornamentals, fruit trees, and conifers. Control of mosses in ornamental and sports turf, on paths and non-crop land, and in glasshouses. Former use.

Registry Numbers and Inventories.
CAS
1982-47-4
EC (EINECS/ELINCS)
217-843-7
RTECS
YS6125000
RTECS class
Agricultural Chemical and Pesticide; Mutagen; Reproductive Effector
Beilstein/Gmelin
2814275
EPA OPP
25501
Swiss Giftliste 1
G-1414
Austrailia AICS
Listed

Properties.
Formula
C15H15ClN2O2
Formula mass
290.77
Melting point, °C
151
Boiling point, °C
414
Vapor pressure, mmHg
4E-9
Density
1.34 g/cm3 (20 C)
Solubility in water
4 mg/L at 20 C
Partition coefficient, pKow
3.57

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
The use of personal protective equipment such as glasses, synthetic gloves and face masks is important.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
(Non-Specific -- Pesticide, Solid, n.o.s.) Do not touch spilled material; stop leak if you can do it without risk. Use water spray to reduce vapors. Small spills: take up with sand or other noncombustible absorbent material and place into containers for later disposal. Small dry spills: with clean shovel place material into clean, dry container and cover; move containers from spill area. Large spills: dike far ahead of spill for later disposal. Use caution with this material.
Stability
Very stable under normal conditions. Sensitive to light. Tenoran 50 wettable powder shows no hygroscopic tendencies and can therefore be stored for long periods even in tropical climates. Decomposed by UV light. Hydrolyzed to 4-(p-chlorophenoxy)aniline in strong acids and alkalis. No significant hydrolysis occurred at 30 C at pH 1.Ultraviolet source of 300w caused 90% loss in 13 hr under controlled conditions.

Fire.
Fire fighting
(Non-Specific -- Pesticide, Solid, n.o.s.) Avoid breathing vapors or dust. Wear self-contained (positive pressure if available) breathing apparatus and full protective clothing.(Non-Specific -- Pesticide, Solid, n.o.s.) For small fires, use dry chemical, carbon dioxide, water spray, or foam. For large fires, use water spray, fog, or foam.
Fire potential
Nonflammable.

Health.
Poison_Class
3
Exposure effects
CNS depression and coma were produced in animals by chloroxuron. No reproductive studies were found.
   Ingestion
Nausea, vomiting, and diarrhea may be noted following ingestion.
   Inhalation
Irritation may occur with high inhalation exposure.
   Skin
Cyanosis unresponsive to oxygen therapy may be noted in patients with methemoglobinemia due to absorption of excessive amounts of these agents.

First aid
 
   Ingestion
The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and jewelry. Wash the skin, including hair and nails, vigorously; do repeated soap washings. Discard contaminated clothing.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
USCG CHRIS Code
CXR