Cholesterol

  • Cholest-5-en-3beta-ol
Formula
C27H46O
Structure
Description
White, near odorless powder.
Uses
Pharmaceutic aid (emulsifying agent).

Registry Numbers and Inventories.
CAS
57-88-5
EC (EINECS/ELINCS)
200-353-2
RTECS
FZ8400000
RTECS class
Tumorigen; Mutagen; Reproductive Effector; Natural Product
Merck
13,2221
Beilstein/Gmelin
1915888
Beilstein Reference
4-06-00-04000
Swiss Giftliste 1
G-7956
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C27H46O
Formula mass
386.66
Melting point, °C
147
Boiling point, °C
360
Vapor pressure, mmHg
0.002 (137 C)
Density
1.046 g/cm3
Solubility in water
Insoluble
Partition coefficient, pKow
9.85
Heat of vaporization
85.9 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container. Keep from contact with oxidizing materials.
Handling
Use with adequate ventilation. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions. Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions.
Stability
Stable under normal shipping and handling conditions.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, irritating and toxic gases, carbon dioxide.

Fire.
Flash Point,°C
209
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode in the heat of a fire. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. Extinguishing media: Use water spray to cool fire-exposed containers. In case of fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Health.
Poison_Class
-
Exposure effects
   Ingestion
Ingestion of large amounts may cause gastrointestinal irritation. Expected to be a low ingestion hazard.
   Inhalation
May cause respiratory tract irritation. Low hazard for usual industrial handling.
   Skin
May cause skin irritation. Low hazard for usual industrial handling.
   Eyes
May cause eye irritation. Dust may cause mechanical irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.

Transport.