Choline hydrogen tartrate

  • Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with [R-(R*,R*)]-2,3-dihydroxybutanedioic acid (1:1)
  • Choline bitartrate
Formula
C5H14NO.C4H5O6
Structure
Description
Free flowing, white crystalline powder.
Uses
Medication.

Registry Numbers and Inventories.
CAS
87-67-2
EC (EINECS/ELINCS)
201-763-4
Beilstein/Gmelin
4064889
Swiss Giftliste 1
G-7957
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Korea ECL
Listed

Properties.
Formula
C5H14NO*C4H5O6
Formula mass
253.25
Melting point, °C
150

Hazards and Protection.
Storage
Keep tightly closed in a cool place in a tightly closed container.
Handling
Containers of this material may be hazardous when emptied. Since emptied containers retain product residues (vapor, liquid, and/or solid), all hazard precautions given in the data sheet must be observed.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
3M Dust respirator No. 8710 or 9900 is recommended or a NIOSH/MSHA jointly approved dust respirator.
Small spills/leaks
Small Spill - Sweep up material for disposal or recovery. Large Spill - Shovel material into containers. Thoroughly sweep area of spill to clean up any residual material.
Stability
Stable.
Incompatibilities
Strong oxidizing agents.
Decomposition
Oxides of carbon.

Fire.
Fire fighting
Extinguish fire using regular foam, water fog, carbon dioxide, sand. Wear a self-contained breathing apparatus with a full facepiece operated in the positive pressure demand mode with appropriate turn-out gear and chemical resistant personal protective equipment.
Hazards
Dusts can form explosive mixtures in air.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Poison_Class
4
Exposure effects
   Ingestion
Nausea, vomiting, abdominal pain, diarrhea, or belching may be noted.
   Inhalation
Dyspnea, bronchospasm, tachypnea, increased bronchial secretions, and pulmonary edema may occur, especially in asthmatic patients.
   Skin
Unlikely to cause skin irritation or injury
   Eyes
Dust can cause eye irritation. Symptoms include stinging, tearing, redness, and swelling of eyes.

First aid
 
   Ingestion
Induction of vomiting is usually not necessary due to spontaneous vomiting. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Bethanechol - for substantial ingestions of bethanechol, consider gastric lavage preceded by endotracheal intubation. Other agents - carbachol, acetylcholine, and pilocarpine are liquids, rapidly absorbed and probably not removed significantly by gastric emptying procedures. Atropine sulfate is the drug of choice. For significant muscarinic symptoms administer: adults - 2 to 4 mg iv, repeated every 3 to 60 minutes as needed to control symptoms, then prn for 24 to 48 hours. Child - 0.04 To 0.08 Mg/kg iv (up to 4 mg) repeated every 5 to 60 minutes as necessary. Epinephrine - may assist in overcoming severe cardiovascular or bronchoconstrictor responses (dose: 0.1 To 1.0 Mg sc).
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.