Cinobufotalin

  • 5-b-Bufa-20,22-dienolide, 14,15-b-epoxy-3-b,5,16-b-trihydroxy, 16-acetate
  • 14,15-Epoxy-14H-cyclopenta[a]phenanthrene, bufa-20,22-dienolide deriv.
Formula
C26H34O7
Structure

Registry Numbers and Inventories.
CAS
1108-68-5
26/27/28
22 36/37/39 45
RTECS
EI2991000
UN (DOT)
2811
Merck
12,2367

Properties.
Formula
C26H34O7
Formula mass
458.55
Melting point, °C
259 - 262
Boiling point, °C
627
Vapor pressure, mmHg
2.3E-18 (25 C)
Density
1.34 kJ/mol
Solubility in water
0.73
pKa/pKb
14.67 (pKa)
Partition coefficient, pKow
0.87
Heat of vaporization
106/4 kJ/mol

Hazards and Protection.
Storage
Store at 2 - 8 C.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
Respirators
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator.
Small spills/leaks
Carefully sweep up and remove. Place in appropriate container. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Moisture.
Decomposition
Oxides of carbon.

Fire.
Flash Point,°C
210
Fire fighting
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
3
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
May be fatal if inhaled, swallowed, or absorbed through skin. Toad venoms are cardioactive and can cause death by disturbing the normal heart rhythm. The mucous membrane that lines the mouth is a means of introducing the venom into the bloodstream. (Venomous Animals and Their Venoms, vol. II: Bucherl, W. Editor).

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
I