Citrazinic acid

  • 2,6-Dihydroxyisonicotinic acid
  • 2,6-Dihydroxy-4-carboxypyridine
  • Isonicotinic acid, 2,6-dihydroxy
  • Isonicotinic acid, 1,2-dihydro-6-hydroxy-2-oxo
  • 4-Pyridinecarboxylic acid, 1,2-dihydro-6-hydroxy-2-oxo
Formula
C6H5NO4
Structure
Description
Beige slightly brown.

Registry Numbers and Inventories.
CAS
99-11-6
EC (EINECS/ELINCS)
202-731-2
R 36/37/38
RTECS
NS1400000
RTECS class
Other
Merck
13,2349
Beilstein/Gmelin
383736
Beilstein Reference
5-22-07-00024
Swiss Giftliste 1
G-3256
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H5NO4
Formula mass
155.11
Melting point, °C
> 330
Density
1 g/cm3
Solubility in water
Very soluble
pKa/pKb
2.14 (pKa)
Partition coefficient, pKow
0.91

Hazards and Protection.
Storage
Store in a cool, dry place. Keep container closed when not in use.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Health.
Poison_Class
4
Exposure effects
   Ingestion
Causes gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
May cause allergic respiratory reaction. May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema.
   Skin
Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
HS Code
2933 39 99