White crystals from ethanol-methylene chloride. Faint odor.
Registry Numbers and Inventories.
Drug; Mutagen; Reproductive Effector; Human Data
Melting point, °C
Boiling point, °C
Solubility in water
Partition coefficient, pKow
Heat of fusion
Heat of vaporization
Hazards and Protection.
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Strong oxidizing agents.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Reduced body temperature, respiratory depression, abnormally low blood pressure and low heart rate have been reported in overdose. ataxia, lethargy, sleepiness and slurred speech are common. Coma has been reported. Benzodiazepines may induce or worsen dyskinesia. Patients may be agitated (paradoxical effect) or disorientated, and may experience memory loss, confusion, and difficulty concentrating. Benzodiazepines are excreted in breast milk and may produce effects in the nursing infant. <br>Administration of benzodiazepines prior to delivery may produce signs of poisoning in the neonate. A condition called floppy infant syndrome, characterized by hypotonia that may last several days, may may occur following maternal diazepam use.
Nausea and vomiting have been reported.
Bullae have been reported.
For pure benzodiazepine ingestions, effects should be minimal, but may include prolonged dialation of the pupils, nystagmus, and divergence paralysis. Constriction of the pupil is also observed.
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.