Cocaethylene

  • 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, ethyl ester, (1R-(exo,exo))
  • Cocaethyline
  • Cocethyline
  • Ethylbenzoylecgonine
  • Homocaine
  • Homococaine
Formula
C18H23NO4
Structure
Description
White powder.

Registry Numbers and Inventories.
CAS
529-38-4
RTECS
CL5602980
Merck
12,2516
Beilstein/Gmelin
6117763
Beilstein Reference
0-22-00-00209

Properties.
Formula
C18H23NO4
Formula mass
317.38
Melting point, °C
109
Boiling point, °C
409
Vapor pressure, mmHg
6.8E-7 (25 C)
Density
1.20 g/cm3 (20 C)
Solubility in water
Insoluble
pKa/pKb
4.96 (pKb)
Partition coefficient, pKow
3.61
Heat of vaporization
66.1 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry, secure location with controlled access. Keep container tightly closed.
Protection
Wear self-contained breathing apparatus, rubber boots, heavy rubber gloves and protective work clothing.
Respirators
Use NIOSH/MSHA approved respirator.
Small spills/leaks
Avoid raising dust, sweep up, place in a bag for waste disposal.
Stability
Stable at normal temperatures and pressures. Material is air and light sensitive.
Incompatibilities
Alkali metal salts, calomel, mercuric oxide, soluble silver salts, iodides and tannic acid.
Decomposition
Oxides of carbon and nitrogen.

Fire.
Flash Point,°C
201
Fire fighting
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear a self-contained breathing apparatus and protective clothing.

Health.
Exposure effects
May be harmful by inhalation, ingestion or skin absorption. May cause allergic reaction, CNS stimulation. May cause sympathetic overactivity with simultaneous depression of the cardiovascular system. Arrhythmias and cardiac arrest/death. Prolonged or repeated exposure may lead to habituation and addiction. Symptoms include irritation, dilation and immobility of eye pupils, euphoria, breathing difficulty, nervousness, restlessness, hypertension, fainting, paleness, breathing arrest, and convulsions.

First aid
 
   Ingestion
Wash out mouth with water if conscious. Seek immediate medical attention.
   Inhalation
Remove to fresh air. Seek immediate medical attention.
   Skin
Flush with copious amounts of water for 15 minutes. Seek immediate medical attention.
   Eyes
Flush with copious amounts of water for 15 minutes. Seek immediate medical attention.

Transport.