Coumatetralyl

  • 3-(a-Tetralinyl)-4-hydroxycoumarin
  • 3-(a-Tetralyl)-4-Hydroxycoumarin
  • 3-(1,2,3,4-Tetrahydro-1-naphthyl)-4-hydroxycoumarin
  • 2H-1-Benzopyran-2-one, 4-hydroxy-3-(1,2,3,4-tetrahydro-1-naphthalenyl)-
  • Endrocide
  • Rodentin
Formula
C19H16O3
Structure
Description
Yellowish-white crystalline powder; colorless when pure; odorless.
Uses
Anticoagulant rodenticide which does not induce bait shyness.

Registry Numbers and Inventories.
CAS
5836-29-3
EC (EINECS/ELINCS)
227-424-0
EC Index Number
607-059-00-7
EC Class
Very toxic; Toxic; Dangerous for the Environment
RTECS
GN7630000
RTECS class
Agricultural Chemical and Pesticide
Beilstein/Gmelin
1323631
EPA OPP
496100
Swiss Giftliste 1
G-1446
Austrailia AICS
Listed
New Zealand
Listed
Korea ECL
Listed

Properties.
Formula
C19H16O3
Formula mass
292.35
Melting point, °C
176.1
Solubility in water
Insoluble
pKa/pKb
4.50 (pKa)
Partition coefficient, pKow
3.86

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
(Non-Specific -- Coumarin Derivative Pesticide, Solid, n.o.s.) Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Remove and isolate contaminated clothing at the site. Do not touch spilled material. Use water spray to reduce vapors. With clean shovel place material into clean, dry container and cover. Dike far ahead of large spills for later disposal.
Stability
No data.
Incompatibilities
Reacts with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat Incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides Reacts violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.

Fire.
Fire fighting
(Non-Specific -- Coumarin Derivative Pesticide, Solid, n.o.s.) Stay upwind; keep out of low areas. Wear positive pressure breathing apparatus and special protective clothing. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material.(Non-Specific -- Coumarin Derivative Pesticide, Solid, n.o.s.) Small fires: dry chemical, carbon dioxide, water spray or foam. Large fires: water spray, fog or foam.
Fire potential
This material may burn but does not ignite readily.
Hazards
This material Fire and runoff from fire control water may produce irritating or poisonous gases. Runoff from fire control water may give off poisonous gases. Container may explode in heat of fire. Enolic form of compound has acidic properties and can form salts with metals.

Health.
Poison_Class
2
Exposure effects
   Ingestion
Spontaneous emesis may occur.
   Inhalation
Overdosage with anticoagulants may cause acute bleeding. Pre-existing blood clotting disease or liver disease may be aggravated by exposure.
   Skin
Ecchymoses and hematomas occur due to reduced clotting capacity.
   Eyes
See inhalation

First aid
 
   Ingestion
Emesis is contraindicated in patients with a prolonged pt or inr due to the risk of bleeding following ipecac-induced increased intracranial pressure. Ipecac may be indicated in the home setting for pediatric patients with an accurate history of recent one-time acute ingestion of these rodenticides. Emesis: use is controversial. May be indicated in the prehospital setting if administered soon (within 30 minutes) after substantial ingestion.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Vitamin k1 (phytonadione) - is a specific antidote and should be administered to any patient with a prolonged pt.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Follow treatment recommendations in the dermal exposure section when appropriate.

Transport.
USCG CHRIS Code
CMT