Cresols (all isomers)

  • Cresylol
  • Hydroxytoluene
  • Methylphenol
  • Tricresol, mixture of isomers
  • ar-Toluenol
Formula
C7H8O
Structure
Description
Yellowish to pinkish liquid which darkens on exposure to light or air. Phenolic odor. Hygrosocopic.
Uses
Disinfectant, bacteriostatic agent and fumigant. Used in the manufacture of dyes, phenolic plastics and paints.

Registry Numbers and Inventories.
CAS
1319-77-3
EC (EINECS/ELINCS)
215-293-2
EC Index Number
604-004-00-9
EC Class
Toxic. Corrosive. [T;C].(15)
RTECS
GO5950000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Human Data
UN (DOT)
2022
Merck
12,2645
Beilstein/Gmelin
8189523
RCRA
U052
EPA OPP
22101
Swiss Giftliste 1
G-2338
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C7H8O
Formula mass
108.15
Melting point, °C
11 - 35
Boiling point, °C
185 - 205
Vapor pressure, mmHg
0.1 (25 C)
Vapor density (air=1)
3.72
Odor Threshold Odor threshold 5 ppm
Density
1.03-1.047 g/cm3 (20 C)
Solubility in water
20 g/L
Viscosity
4.49-7.0 centipoises at 40 C
Surface tension
37 g/s2 20 C
Partition coefficient, pKow
1.94 - 1.96
Heat of vaporization
50.2 kJ/mol
Heat of combustion
-3700 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Corrosives area.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Discard contaminated shoes.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong acids, bases, alliphatic amines, oxidizing agents (strong, e.g. bromine, hydrogen peroxide, nitrogen dioxide, potassium nitrate), chlorosulfonic acid, oleum.
Decomposition
Carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
81
Autoignition, °C
559
Lower exp. limit, %
1.1
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray.
Fire potential
This material is combustible.
Hazards
Sealed closed containers can build up pressure if exposed to heat.
Combustion products
Flammable toxic vapors are given off in a fire.
Health
3
 
Flammability
2
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV: 5 ppm; 22 mg/m3 (skin) (ACGIH 1991-1992). OSHA PEL: TWA 5 ppm (22 mg/m3) skin NIOSH REL: TWA 2.3 ppm (10 mg/m3) NIOSH IDLH: 250 ppm
Poison_Class
3
Exposure effects
Prolonged or repeated skin contact may cause dermatitis. May cause liver and kidney damage. May cause digestive tract disturbances. Repeated exposure may cause central nervous system damage.
   Ingestion
May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns. May cause liver and kidney damage. May be harmful if swallowed. May cause central nervous system depression, convulsions, coma, and possible death due to respiratory paralysis.
   Inhalation
Causes severe irritation of upper respiratory tract with coughing, burns, breathing difficulty, and possible coma. May cause effects similar to those described for ingestion.
   Skin
Causes severe skin irritation and burns. May be harmful if absorbed through the skin.
   Eyes
Causes eye burns. May result in corneal injury. May cause conjunctivitis and keratitis.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Discard contaminated clothing in a manner which limits further exposure. Destroy contaminated shoes.
   Eyes
Get medical aid immediately. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
2022
Response guide
Hazard class
6.1
Packing Group
II
 
USCG CHRIS Code
CRS
 
21 Phenols, Cresols
Std. Transport #
4921706
 
IMO Chemical Code
17