Crufomate

  • Amidophos
  • 4-tert-Butyl-2-chlorophenyl methyl methylphosphoramidate
Formula
C12H19ClNO3P
Structure
Description
White crystalline solid.
Uses
Former use insecticide for cattle grubs, horn flies & lice on cattle.

Registry Numbers and Inventories.
CAS
299-86-5
EC (EINECS/ELINCS)
206-083-1
EC Index Number
015-074-00-X
EC Class
Harmful; Dangerous for the Environment
RTECS
TB3850000
RTECS class
Agricultural Chemical and Pesticide; Reproductive Effector
UN (DOT)
2783
Merck
12,2671
Beilstein/Gmelin
2133258
Beilstein Reference
4-06-00-03312
EPA OPP
12101
Swiss Giftliste 1
G-2505

Properties.
Formula
C12H19ClNO3P
Formula mass
291.71
Melting point, °C
61.5 - 62
Boiling point, °C
117 - 118 (0.01 torr)
Vapor pressure, mmHg
0.001
Density
1.1618 g/cm3 (20 C)
Solubility in water
Insoluble
Refractive index
1.5142 (20 C)

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
Relatively stable at pH 7.0 Or below and unstable in strongly acid media unstable over long periods in water preparations, at temperatures above 60 C, and in alkali. Unstable over long periods in aqueous preparations or above 140 degrees f.
Incompatibilities
Avoid contact with strongly alkaline and strongly acidic media.
Decomposition
When heated to decomposition it emits very toxic fumes of phosphorus oxides, nitrogen oxides and cl-.

Fire.
Fire fighting
Use method most appropriate to fight surrounding fire.
Fire potential
Non-Combustible
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure limit(s)
TLV: ppm; 5 mg/m3 (as TWA) (ACGIH 1995-1996). NIOSH REL: TWA 5 mg/m3 ST 20 mg/m3
Poison_Class
4
Exposure effects
Reduced body temperature or elevated body temperature may occur. Low heart rate and abnormally low blood pressure may develop after moderate to severe poisoning. Rapid heart rate, elevated blood pressure, and changes in respiratory rate may also occur. Early giddiness, anxiety headache, and restlessness followed by ataxia, drowsiness, and confusion are common with moderate to severe exposures. Sporadic reports of human birth defects related to organophosphates have not been fully verified.
   Ingestion
Nausea, vomiting, abdominal cramps, and diarrhea are common muscarinic effects. Both painless and frank clinical pancreatitis have been reported.
   Inhalation
Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Effects of contact or inhalation may be delayed.
   Skin
Profuse sweating is common. Pallor may be noted. Dermal sensitization has been reported. May be absorbed through the skin.
   Eyes
Constriction of the pupil, tearing, and blurred vision are common. Prolonged dialation of the pupils may occur. Salivation commonly occurs.

First aid
 
   Ingestion
Seek medical assistance.
   Inhalation
Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.
   Skin
Remove and isolate contaminated clothing and shoes. Remove material from skin immediately. Immediately flush with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin.
   Eyes
Immediately flush with running water for at least 20 minutes.

Transport.
UN number
2783
Response guide
Hazard class
6.1
Packing Group
I; II; III