Curine

  • (-)-Bebeerine
  • Tubocuraran-7',12'-diol, 6,6'-dimethoxy-2,2'-dimethyl-, (1b)
  • 13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido[3',2':14,15][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline-9,19-diol, 2,3,13a,14,15,16,25,25a-octahydro-18,29-dimethoxy-1,14-dimethyl-, (13aR,25aR)-
  • Aristolochine
Formula
C36H38N2O6
Structure
Description
White solid.

Registry Numbers and Inventories.
CAS
436-05-5
EC (EINECS/ELINCS)
207-109-4
26/27/38
22 36/37/39 45
UN (DOT)
1544
Merck
12,2745

Properties.
Formula
C36H38N2O6
Formula mass
594.71
Melting point, °C
215
Vapor pressure, mmHg
1.3E-20 (25 C)
Density
1.24 g/cm3 (20 C)
Solubility in water
6.5 mg/L (25 C)
pKa/pKb
6.29 (pKb)
Partition coefficient, pKow
4.12
Heat of vaporization
107.0 kJ/mol

Hazards and Protection.
Storage
Store at 2 - 8 C.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
Respirators
Wear appropriate government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.

Fire.
Fire fighting
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
3
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
May cause irritation. May be fatal if inhaled, swallowed, or absorbed through skin. Targets autonomic nervous system, skeletal muscle. May be fatal if enters bloodstream.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.
UN number
1544
Response guide
Hazard class
6.1
Packing Group
II