Cyanoacetic acid

  • Malonic mononitrile
Formula
N CCH2COOH
Structure
Description
Yellow-brown liquid with an unpleasant odor.
Uses
Synthesis of intermediates, manufacture barbital.

Registry Numbers and Inventories.
CAS
372-09-8
EC (EINECS/ELINCS)
206-743-9
EC Class
harmful, corrosive, dangerous for the environment
R 20/21/22 34
S 26 36/37/39 45
RTECS
AG3675000
RTECS class
Other
UN (DOT)
3261
Merck
13,2718
Beilstein/Gmelin
506325
Beilstein Reference
4-02-00-01888
Swiss Giftliste 1
G-1449
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C3H3NO2
Formula mass
85.06
Melting point, °C
66
Boiling point, °C
319
Vapor pressure, mmHg
8E-5 (25 C)
Density
> 1.1 g/cm3 (20 C) (solid)
Solubility in water
Very soluble
pKa/pKb
2.45 (pKa)
Partition coefficient, pKow
-0.76
Heat of vaporization
61.6 kJ/mol
Heat of combustion
-1233 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Keep container closed when not in use. Store in a tightly closed container. Corrosives area.
Handling
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Take precautionary measures against static discharges. Keep container tightly closed. Do not get on skin or in eyes. Use with adequate ventilation. Use only in a chemical fume hood. Discard contaminated shoes.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Disposal code
4
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide, acetonitrile.

Fire.
Flash Point,°C
108
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. Containers may explode if exposed to fire. Extinguishing media: Cool containers with flooding quantities of water until well after fire is out. In case of fire use dry chemical, dry sand, or carbon dioxide.
Fire potential
Very flammable.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Toxic oxides of nitrogen and toxic and flammable acetonitrile vapors may form in fire.
Health
3
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
3
Exposure effects
Headache, dizziness, confusion, agitation, weakness, seizures, and coma have been reported.
   Ingestion
May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. May be harmful if swallowed.
   Inhalation
May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema. Causes chemical burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema.
   Skin
Causes skin burns.
   Eyes
Causes eye burns.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
3261
Response guide
Hazard class
8
Packing Group
I; II; III
 
USCG CHRIS Code
CYA
 
HS Code
2926 90 95