Cyanocobalamin

  • Anacobin
  • Cobamide, cyano-5,6-dimethyl-1H-benzimidazole
  • Vitamin B 12
Formula
C63H88CoN14O14P
Structure
Description
Dark red crystals or an amorphous or crystalline red powder. Odorless.
Uses
Medication.

Registry Numbers and Inventories.
CAS
68-19-9
EC (EINECS/ELINCS)
200-680-0
RTECS
GG3750000
RTECS class
Drug; Mutagen; Reproductive Effector
Merck
12,10152
Beilstein/Gmelin
4122889
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Korea ECL
Listed

Properties.
Formula
C63H88CoN14O14P
Formula mass
1355.38
Solubility in water
12.5 g/L

Hazards and Protection.
Storage
Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture. Store protected from light.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Avoid ingestion and inhalation. Store protected from light. Keep from contact with moist air and steam.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation. Do not get water inside containers.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizers, strong acids.
Decomposition
Carbon monoxide, oxides of nitrogen, oxides of phosphorus, carbon dioxide, oxides of cobalt.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam. Do NOT get water inside containers.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
May cause cancer according to animal studies. Repeated exposure may cause sensitization dermatitis. Animal studies have reported that fetal effects/abnormalities may occur when maternal toxicity is seen. Cobalt compounds may cause cancer based upon animal studies.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Ingestion of large amounts may cause convulsions, tremors, muscular contractions or spasticity, diarrhea, or fever.
   Inhalation
May cause respiratory tract irritation.
   Skin
May cause skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
   Eyes
Contact may cause transient eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid if irritation develops or persists. Wash clothing before reuse. Flush skin with plenty of soap and water.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
HS Code
2936 26 00