Cyclazocine

  • 2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-3-(cyclopropylmethyl)-6,11-dimethyl
Formula
C18H25NO
Structure
Description
White powder.
Uses
Sigma receptor agonist that is also an agonist atkreceptors and an antagonist atµ receptors.

Registry Numbers and Inventories.
CAS
3572-80-3
EC (EINECS/ELINCS)
222-689-9
RTECS
PB8585000
RTECS class
Drug; Reproductive Effector
Merck
12,2773
Beilstein/Gmelin
4144916
Beilstein Reference
5-21

Properties.
Formula
C18H25NO
Formula mass
271.4
Melting point, °C
194 - 195
Boiling point, °C
399
Vapor pressure, mmHg
6E-7 (25 C)
Solubility in water
Insoluble
pKa/pKb
4.82 (pKb)
Heat of vaporization
67.5 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed. Store in the dark. Store at 2-8 C
Protection
Exercise appropriate precautions to minimize direct contact with skin or eyes and prevent inhalation of dust.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Photosensitive material.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.

Fire.
Flash Point,°C
189
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Avoid contact and inhalation.
   Ingestion
May be harmful if swallowed.
   Inhalation
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
   Skin
May cause skin irritation. May be harmful if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.