Cycloate

  • S-Ethyl cyclohexylethyl carbamothioate
  • S-Ethyl cyclohexylethylthiocarbamate
  • S-Ethyl N-cyclohexyl-N-ethyl(thiocarbamate)
  • S-Ethylethylcyclohexylthiocarbamate
  • S-Ethyl n-ethyl N-cyclohexylthiolcarbamate
  • S-Ethyl n-ethylthiocyclohexanecarbamate
Formula
C11H21NOS
Structure
Description
Clear liquid. Aromatic.
Uses
Preplant for annual grasses, nutgrass, certain perennial grasses, many broadleafweeds in sugar beets, table beets, spinach.

Registry Numbers and Inventories.
CAS
1134-23-2
EC (EINECS/ELINCS)
214-482-7
RTECS
GU7200000
RTECS class
Agricultural Chemical and Pesticide; Mutagen
Beilstein/Gmelin
2937178
RCRA
U386
EPA OPP
41301
Swiss Giftliste 1
G-6497

Properties.
Formula
C11H21NOS
Formula mass
215.39
Melting point, °C
12
Boiling point, °C
303
Vapor pressure, mmHg
0.001 (25 C)
Density
1.024 g/cm3 (20 C)
Solubility in water
75 mg/L (20 C)
Partition coefficient, pKow
3.83
Heat of vaporization
54.3 kJ/mol

Hazards and Protection.
Storage
Store away from feed, foodstuffs and out of the reach of children.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate clothing to prevent any reasonable probability of skin contact. Wear eye protection to prevent any possibility of eye contact.
Respirators
Any self-contained breathing apparatus with a full facepiece and operated in a pressure-demand or other positive pressure mode; or any supplied-air respirator with a full facepiece and operated in a pressure-demand or other positive pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive pressure mode.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
Stable, 50% unchanged greater than 10 yr at 70 C. Hydrolyzed by strong acids and alkalis. Thermally Stable to heating to 100 C for 16 hr.
Incompatibilities
Incompatible with acids, peroxides, and acid halides.

Fire.
Flash Point,°C
139
Fire fighting
Wear self-contained breathing apparatus with a full facepiece operated in pressure-demand or other positive pressure mode when fighting fire. Extinguish fire using agent suitable for type of surrounding fire. Material itself does not burn or burns with difficulty.

Health.
Poison_Class
4
Exposure effects
Exposure to thiram or mbdt-carb (based on animal studies) may cause weakness, ataxia, ascending paralysis and hypothermia. Peripheral neuropathy (pain, numbness and weakness of the extremities) has been noted following exposure to thiuram (the ethyl analog of thiram). No adverse reproductive effects (testicular parameters) in male mice were observed following methyl thiophanate doses up to 1000 mg/kg orally for 5 consecutive days (Traina et al, 1998). Maternal toxicity was evident in female rats.
   Ingestion
Nausea, vomiting and diarrhea may occur.
   Inhalation
Respiratory failure, requiring ventilatory support, has been reported following ingestions.
   Skin
Exposure to dusts, sprays, solutions, wettable powder suspensions or emulsions of these agents may lead to skin and mucous membrane irritation.

First aid
 
   Ingestion
Ipecac induced vomiting is not recommended because of the potential for cns depression and seizures. Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Intravenous fluids may be useful in restoring extracellular fluid volume following severe vomiting and diarrhea. Oxygen therapy is effective in relieving the distress of antabuse-like reactions rarely associated with exposure to thiram and possibly the mbdt-carb compounds. No specific antidotes are available for poisoning by these compounds. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.