Cyclohexanone oxime

  • (Hydroxyimino)cyclohexane
  • Antioxidant D
Formula
C6H10(=NOH)
Structure
Description
Prisms, liquid or light tan crystalline solid.
Uses
In prepn of caprolactam. Antioxidant.

Registry Numbers and Inventories.
CAS
100-64-1
EC (EINECS/ELINCS)
202-874-0
EC Class
harmful
S 22 36/37
RTECS
GW1925000
RTECS class
Tumorigen; Drug; Mutagen
Beilstein/Gmelin
1616769
Beilstein Reference
4-07-00-00021
Swiss Giftliste 1
G-4423
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C6H11NO
Formula mass
113.16
Melting point, °C
88 - 90
Boiling point, °C
206
Vapor pressure, mmHg
0.03 (25 C)
Vapor density (air=1)
3.9
Density
1.13 g/cm3 (20 C)
Solubility in water
15 mg/L
pKa/pKb
11.81 (pKa)
Heat of fusion
12.5 kJ/mol
Heat of vaporization
58.08 kJ/mol
Heat of combustion
-3778 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions. Provide ventilation.
Disposal code
3
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents - strong acids.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
110
Autoignition, °C
315
Upper exp. limit, %
9.8
Lower exp. limit, %
1.3
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.
Fire potential
This material is probably combustible.

Health.
Poison_Class
4
Exposure effects
Prolonged exposure may cause anemia and methemoglobinemia, characterized by dizziness, drowsiness, headache, breath shortness, cyanosis, rapid heart rate and chocolate-brown colored blood.
   Ingestion
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver damage. May cause spleen damage.
   Inhalation
May cause respiratory tract irritation.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
HS Code
2928 00 90