Cyclohexanone

  • Ketohexamethylene
  • Pimelic ketone
  • Cyclohexyl ketone
Formula
C6H10=O
Structure
Description
Colorless to pale yellow oily liquid with a sweet, sharp, mildly pleasant odor like acetone and peppermint.
Uses
Solvent.

Registry Numbers and Inventories.
CAS
108-94-1
EC (EINECS/ELINCS)
203-631-1
EC Index Number
606-010-00-7
EC Class
Flammable; Harmful
R 10 20
RTECS
GW1050000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Human Data; Primary Irritant
UN (DOT)
1915
Merck
13,2755
Beilstein/Gmelin
385735
Beilstein Reference
4-07-00-00015
RCRA
U057
EPA OPP
25902
Swiss Giftliste 1
G-1458
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H10O
Formula mass
98.15
Melting point, °C
-31
Boiling point, °C
155.6
Vapor pressure, mmHg
4.8 (25 C)
Vapor density (air=1)
3.4
Saturation Concentration
5264 ppm (0.53%) at 20 C; 6840 ppm (0.68%) at 25 C (calculated)
Evaporization number
0.29 (butyl acetate = 1); 40.6
Odor Threshold Odor threshold 0.88 ppm
Critical temperature
356
Critical pressure
3.8
Density
0.9478 g/cm3 (20 C)
Solubility in water
87 g/L
Viscosity
2.2 cp (=cp) @ 25C
Surface tension
35.05 g/s2 @ 20 C
Refractive index
1.4507 (20 C)
Dipole moment
2.9 D (20 C)
Dielectric constant
18.3 (25 C)
Partition coefficient, pKow
0.81
Heat of fusion
1.5 kJ/mol
Heat of vaporization
45.1 kJ/mol
Heat of combustion
-3483 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
B3 D1B D2B
Handling
Wash thoroughly after handling. Use with adequate ventilation. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A half-face organic vapor respirator may be worn for up to ten times the exposure limit, or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. A full-face piece organic vapor respirator may be worn up to 50 times the exposure limit, or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Scoop up with a nonsparking tool, then place into a suitable container for disposal. Remove all sources of ignition. Provide ventilation. Clean up residual material by washing area with a 2-5% solution of soda ash.
Stability
Stable under normal temperatures and pressures. Forms explosive mixture with air (flash point 70 degrees F).
Incompatibilities
Oxidizing agents, strong acids, amines, nitric acid, plastics, rubber, sulfuric acid, alliphatic amines, lead, red metals , resins.
Decomposition
Carbon monoxide, carbon dioxide, toxic gases.

Fire.
Flash Point,°C
43
Autoignition, °C
420
Upper exp. limit, %
9.4
Lower exp. limit, %
1.1
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use water spray to cool fire-exposed containers. Water may be ineffective. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water. For small fires, use carbon dioxide, dry chemical, dry sand, or alcohol-resistant foam. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
HIGHLY FLAMMABLE.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. May polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
2
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV (as TWA): 25 ppm; 100 mg/m3 A4 (skin) (ACGIH 1997). OSHA PEL: TWA 50 ppm (200 mg/m3) NIOSH REL: TWA 25 ppm (100 mg/m3) skin NIOSH IDLH: 700 ppm
Poison_Class
4
Exposure effects
Prolonged or repeated skin contact may cause defatting and dermatitis. Prolonged exposure may cause non-specific nervous system effects.
   Ingestion
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. May be harmful if swallowed.
   Inhalation
Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. May cause liver and kidney damage. May cause narcotic effects in high concentration. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. May cause irritation of the mucous membranes.
   Skin
Causes skin irritation. Harmful if absorbed through the skin.
   Eyes
May result in corneal injury. Vapors may cause eye irritation. Contact produces irritation, tearing, and burning pain.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1915
Response guide
Hazard class
3
Packing Group
III
 
USCG CHRIS Code
CCH
 
HS Code
2914 22 00
 
Std. Transport #
4912079
 
IMO Chemical Code
17
IMO Pollution Category
D
IMO Hazard code
S