Cyclohexylamine

  • Cyclohexanamine
  • Aminocyclohexane
  • Aminohexahydrobenzene
Formula
C6H13N
Structure
Description
Colorless to yellow liquid with a strong, fishy, amine odor.
Uses
In organic synthesis, manufacture insecticides, plasticizers, emulsifying agents, dry-cleaning soaps, acid gas absorbents.

Registry Numbers and Inventories.
CAS
108-91-8
EC (EINECS/ELINCS)
203-629-0
EC Index Number
612-050-00-6
EC Class
Flammable; Harmful; Corrosive
R 10 21/22 34
S 36/37/39 45
RTECS
GX0700000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Primary Irritant
UN (DOT)
2357
Merck
13,2758
Beilstein/Gmelin
471175
Beilstein Reference
4-12-00-00008
Swiss Giftliste 1
G-1462
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H13N
Formula mass
99.18
Melting point, °C
-18
Boiling point, °C
134.5
Vapor pressure, mmHg
8.1 (25 C)
Vapor density (air=1)
3.42
Saturation Concentration
1.41% (20 C) (calculated)
Critical temperature
342
Density
0.88216 g/cm3 (0 C)
Solubility in water
Miscible
Viscosity
0.75 cp (30 C)
Surface tension
33.5 g/s2 (25 C)
Refractive index
1.45949 (15 C)
Dipole moment
1.24 D (20 C)
Dielectric constant
4.55 (20 C)
pKa/pKb
3.30 (pKb)
Partition coefficient, pKow
1.40
Heat of fusion
17.5 kJ/mol
Heat of vaporization
36.1 kJ/mol
Heat of combustion
-4117 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from organic halogens. Flammables-area. Keep away from acids.
B2 D1B D2B E
Handling
Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not get on skin or in eyes. Do not ingest or inhale. Use with adequate ventilation. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin. Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Use water spray to dilute spill to a non-flammable mixture. Clean up spills immediately, using the appropriate protective equipment. Scoop up with a nonsparking tool, then place into a suitable container for disposal. Use water spray to disperse the gas/vapor. Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Disposal code
5
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Nonoxidizing mineral acids, strong acids, organic acids, organic anhydrides, isocyanates, vinyl acetate, acrylates, substituted allyls, alkylene oxides, epichlorohydrin, ketones, aldehydes, alcohols, glycols, phenols, cresol, caprolactam solution, strong oxidizing agents, copper alloys, galvanized steel, zinc.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
31
Autoignition, °C
293
Upper exp. limit, %
9.4
Lower exp. limit, %
1.5
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
Fire potential
Very flammable. Extreme danger-enter with great care.
Hazards
When heated to decomposition, it emits highly toxic fumes. Vapor may travel a considerable distance to source of ignition and flash back. Toxic oxides of nitrogen are produced during combustion. Nitric acid; reacts vigorously with oxiding materials. Stable, avoid physical damage, storage with oxidizing material.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
3
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV: 10 ppm; 41 mg/m3 (as TWA) (ACGIH 1992-1993). PDK: 1 mg/m3 (USSR 1993). NIOSH REL: TWA 10 ppm (40 mg/m3)
Poison_Class
3
Exposure effects
Prolonged or repeated skin contact may cause dermatitis. May cause cancer in humans. May cause reproductive and fetal effects.
   Ingestion
Corrosive. Harmful if swallowed. May cause severe and permanent damage to the digestive tract. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Causes gastrointestinal tract burns. May cause perforation of the digestive tract. Ingestion of large amounts may cause CNS depression. May cause systemic effects.
   Inhalation
Inhalation can cause severe irritation of mucous membranes and upper respiratory tract. Symptoms may include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea and vomiting. May cause pulmonary edema, a medical emergency.
   Skin
Corrosive. Harmful if absorbed through the skin. Causes skin burns. May cause cyanosis of the extremities. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
   Eyes
Corrosive. Causes eye burns. May cause chemical conjunctivitis and corneal damage.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
2357
Response guide
Hazard class
8
Packing Group
II
 
USCG CHRIS Code
CHA
 
7 Aliphatic amines
HS Code
2921 30 10
 
Std. Transport #
4935212
 
IMO Chemical Code
17
IMO Pollution Category
C
IMO Hazard code
S/P