Cytosine, 5-fluoro

  • Alcobon
  • 4-Amino-5-fluoro-2(1H)-pyrimidinone
  • Ancobon
  • Ancotil
  • 5-FC
  • Flucytosine
Formula
C4H4FN3O
Structure
Uses
Medication.

Registry Numbers and Inventories.
CAS
2022-85-7
EC (EINECS/ELINCS)
217-968-7
S 22 36/37
RTECS
HA6040000
RTECS class
Drug; Mutagen; Human Data
Merck
13,4151
Beilstein/Gmelin
127285
Beilstein Reference
4-25-00-03688

Properties.
Formula
C4H4FN3O
Formula mass
129.09
Melting point, °C
165
Boiling point, °C
298
Decomposition point, °C
295-297
Critical temperature
536
Critical pressure
60.0
Solubility in water
15 g/L
Partition coefficient, pKow
-1.07

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Store protected from light.
Protection
Eyes: Wear chemical goggles. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear a chemical apron.
Respirators
A NIOSH/MSHA approved air purifying dust or mist respirator or European Standard EN 149.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.
Stability
No data.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen fluoride.

Fire.
Flash Point,°C
296
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Health.
Exposure effects
Prolonged or repeated exposure may cause adverse reproductive effects.
   Ingestion
No hazard expected in normal industrial use.
   Inhalation
May cause respiratory tract irritation.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Get medical aid. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.

Transport.