cis-1,2,3,6-Tetrahydrophthalic anhydride

  • cis-1,2,3,6-Tetrahydrophthalic acid anhydride
  • cis-4-Cyclohexene-1,2-dicarboxylic anhydride
  • cis-4-Cyclohexene-1,2-dicarboxylic acid anhydride
  • 1,3-Isobenzofurandione, 3a,4,7,7a-tetrahydro-, (3aR,7aS)-rel-
Formula
C8H8O3
Structure
Description
White flakes.

Registry Numbers and Inventories.
CAS
935-79-5
EC (EINECS/ELINCS)
213-308-7
EC Index Number
607-099-00-5
EC Class
Irritant; Sensitising; Dangerous for the Environment
UN (DOT)
2698
Beilstein/Gmelin
82341
Beilstein Reference
5-17-11-00134
Canada DSL/NDSL
NDSL
US TSCA
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C8H8O3
Formula mass
152.14
Melting point, °C
103 - 104
Boiling point, °C
343
Density
1.402 g/cm3
Solubility in water
Soluble
Partition coefficient, pKow
0.79

Hazards and Protection.
Storage
Keep container closed when not in use. Store protected from moisture.
Handling
Use only in a well ventilated area. Minimize dust generation and accumulation. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Do not allow contact with water. Discard contaminated shoes. Keep from contact with moist air and steam.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation. Do not get water inside containers.
Stability
Stable under normal temperatures and pressures. May decompose on exposure to moist air or water.
Incompatibilities
Moisture, oxidizing agents, strong bases.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
156
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Contact with water forms corrosive vapors. Runoff from fire control or dilution water may cause pollution. Extinguishing media: Use water spray to cool fire-exposed containers. Do NOT get water inside containers. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water. For small fires, use carbon dioxide, dry chemical, dry sand, or alcohol-resistant foam.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure effects
Effects may be delayed.
   Ingestion
May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. May cause perforation of the digestive tract. May cause systemic effects.
   Inhalation
Causes chemical burns to the respiratory tract. Aspiration may lead to pulmonary edema. May cause systemic effects. Exposure may produce metabolic acidosis.
   Skin
Causes skin burns. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
   Eyes
Causes eye burns. May cause chemical conjunctivitis and corneal damage.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
2698
Response guide
Hazard class
8
Packing Group
III