- cis-4-Cyclohexene-1,2-dicarboxylic anhydride
- Tetrahydrophthalic anhydride
- 1,2,3,6-Tetrahydrophthalic anhydride
- 1,3-Isobenzofurandione, 3a,4,7,7a-tetrahydro
White crystalline powder.
Chemical intermediate for light-colored alkylateds, polyesters, plasticizers & adhesives, intermediate for pesticides, hardener for resins.
Registry Numbers and Inventories.
EC Index Number
Irritant; Sensitising; Dangerous for the Environment
R 41 42/43 52/53
S 22 24 26 37/39 61
Swiss Giftliste 1
Japan ENCS (MITI)
Melting point, °C
123 - 126
Boiling point, °C
Vapor pressure, mmHg
0.001 (25 C)
1.375 g/cm3 (25C)
Solubility in water
Partition coefficient, pKow
Heat of vaporization
Hazards and Protection.
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Wear appropriate protective gloves, clothing and goggles.
Wear positive pressure self-contained breathing apparatus (SCBA).
Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Use water spray to knock-down vapors. Neutralize spilled material with crushed limestone, soda ash, or lime.
Reacts with oxidizers Reacts exothermically with water Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases.
Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use alcohol foam, dry chemical or carbon dioxide. Use water spray to knock-down vapors.
Combustible material: may burn but does not ignite readily.
Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas.
Fire will produce irritating, corrosive and/or toxic gases.
Bronchial asthma and upper respiratory irritation may occur and recur for as long as 4 years after avoidance of exposure.
Phthalic acid anhydride is a delayed, direct skin irritant.
Oral effects are unknown. Vomiting is not recommended based on its irritant properties.
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.
2917 20 00
Std. Transport #