cis-1,2,3,6-Tetrahydrophthalic anydride

  • cis-4-Cyclohexene-1,2-dicarboxylic anhydride
  • Tetrahydrophthalic anhydride
  • 1,2,3,6-Tetrahydrophthalic anhydride
  • 1,3-Isobenzofurandione, 3a,4,7,7a-tetrahydro
Formula
C8H8O3
Structure
Description
White crystalline powder.
Uses
Chemical intermediate for light-colored alkylateds, polyesters, plasticizers & adhesives, intermediate for pesticides, hardener for resins.

Registry Numbers and Inventories.
CAS
85-43-8
EC (EINECS/ELINCS)
201-605-4
EC Index Number
607-099-00-5
EC Class
Irritant; Sensitising; Dangerous for the Environment
R 41 42/43 52/53
S 22 24 26 37/39 61
RTECS
GW5775000
RTECS class
Primary Irritant
UN (DOT)
2698
Beilstein/Gmelin
82340
Beilstein Reference
5-17-11-00134
Swiss Giftliste 1
G-6852
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C8H8O3
Formula mass
152.15
Melting point, °C
123 - 126
Boiling point, °C
306
Vapor pressure, mmHg
0.001 (25 C)
Density
1.375 g/cm3 (25C)
Solubility in water
Soluble
Partition coefficient, pKow
0.10
Heat of vaporization
54.6 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Use water spray to knock-down vapors. Neutralize spilled material with crushed limestone, soda ash, or lime.
Disposal code
4
Stability
No data.
Incompatibilities
Reacts with oxidizers Reacts exothermically with water Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases.

Fire.
Flash Point,°C
148
Autoignition, °C
400
Fire fighting
Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use alcohol foam, dry chemical or carbon dioxide. Use water spray to knock-down vapors.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.

Health.
Poison_Class
4
Exposure effects
   Ingestion
See Inhalation.
   Inhalation
Bronchial asthma and upper respiratory irritation may occur and recur for as long as 4 years after avoidance of exposure.
   Skin
Phthalic acid anhydride is a delayed, direct skin irritant.
   Eyes
See Inhalation.

First aid
 
   Ingestion
Oral effects are unknown. Vomiting is not recommended based on its irritant properties.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
2698
Response guide
Hazard class
8
Packing Group
III
 
HS Code
2917 20 00
 
Std. Transport #
4931441