D-Mannitol

  • Isotol
  • D-Manninol
Formula
C6H14O6
Structure
Description
Odorless white crystalline powder or free-flowing granules. Sweet taste.
Uses
Used in the food industry as anti-caking and free flowing agent, stabilizer, thickener, and non-nutritive sweetener.

Registry Numbers and Inventories.
CAS
69-65-8
EC (EINECS/ELINCS)
200-711-8
RTECS
OP2060000
RTECS class
Tumorigen; Drug; Mutagen; Human Data
Merck
13,5769
Beilstein/Gmelin
1721898
Beilstein Reference
4-01-00-02841
Swiss Giftliste 1
G-7750
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H14O6
Formula mass
182.17
Melting point, °C
164 - 169
Boiling point, °C
295
Vapor density (air=1)
1.52
Density
1.49 g/cm3
Solubility in water
Soluble
Refractive index
1.333 (20 C)
pKa/pKb
13.50 (pKa)
Partition coefficient, pKow
-3.10
Heat of fusion
49.8 kJ/mol
Heat of vaporization
135.60 kJ/mol
Heat of combustion
-3050 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Keep from contact with oxidizing materials.
Handling
Use with adequate ventilation. Avoid contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal shipping and handling conditions. Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Oxidizing materials.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam.
Fire potential
This chemical is probably combustible.

Health.
Poison_Class
-
Exposure effects
in overdose lethargy and coma have been reported in children ingesting thiazide diuretics. Altered mental status, headache, hypertonia, muscle weakness, and seizures may develop secondary to diuretic-induced electrolyte abnormalities. Ototoxicity occurs rarely and is usually reversible.
   Ingestion
Ingestion of large amounts may cause gastrointestinal irritation. Expected to be a low ingestion hazard.
   Inhalation
May cause respiratory tract irritation. Low hazard for usual industrial handling.
   Skin
May cause skin irritation. Low hazard for usual industrial handling.
   Eyes
Dust may cause mechanical irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
20. Alcohols. Glycols
HS Code
2905 43 00