D-Methamphetamine

  • anadrex
  • crystal
  • D-Deoxyephedrine
  • (+)-(S)-Deoxyephedrine
  • Desoxyephedrine
  • D-Desoxyephedrine
Formula
C10H15N
Structure
Description
Clear, colorless liquid. Characteristic odor resembling geranium leaves.
Uses
psychostimulant

Registry Numbers and Inventories.
CAS
537-46-2
EC (EINECS/ELINCS)
208-668-7
RTECS
SH4910000
RTECS class
Reproductive Effector; Human Data
UN (DOT)
3259
Merck
12,6015
Beilstein/Gmelin
2207147
Beilstein Reference
4-12-00-02589

Properties.
Formula
C10H15N
Formula mass
149.24
Melting point, °C
170-2
Boiling point, °C
37 - 41 (0.1 torr)
Density
0.9131 g/cm3 (23 C)
Solubility in water
0.5 g/ml
Refractive index
1.5083 (20 C)
pKa/pKb
9.9 (pKa)
Partition coefficient, pKow
2.07

Hazards and Protection.
Storage
Store in airtight containers. Methamphetamine hydrochloride tablets and extended release tablets should be stored in well-closed containers at a temperature less than 40C, preferably at 15-30C.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
ELIMINATE all ignition sources. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
Sensitive to light.

Fire.
Fire fighting
Extinguish using agent most appropriate for surrounding fire.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
Severe elevated body temperature may develop. Elevated blood pressure and rapid heart rate are common. Agitation, confusion, paranoia, delirium, hallucinations, restlessness, hyperactivity, talkativeness, irritability, insomnia, and headache are common. Chorea, dystonia, fasciculations, muscle rigidity, tics, and tremors may develop. Seizures and coma may occur with severe intoxication. Other neurological effects have included stroke and cerebral vasculitis. Serotonin syndrome has occurred.
   Ingestion
Vomiting, diarrhea, cramps, anorexia and gastrointestinal hemorrhage may occur.
   Inhalation
Tachypnea is common. Pulmonary hypertension has been associated with chronic use or abuse which may result from contaminants. Pulmonary edema and ards are unusual complications of severe exposure.
   Skin
The skin is usually flushed and diaphoretic.
   Eyes
See Inhalation.

First aid
 
   Ingestion
Do not induce emesis. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.
   Skin
Remove and isolate contaminated clothing and shoes. Immediately flush with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin.
   Eyes
Immediately flush with running water for at least 20 minutes.

Transport.
UN number
3259
Response guide
Hazard class
8
Packing Group
I; II; III
 
7. Aliphatic amines