DL-1,2:3,4-Diepoxybutane

  • 2,2'-Bioxirane, (2R,2'R)-rel-
  • dl-1,2:3,4-Diepoxybutane
Formula
C4H6O2
Structure
Description
Colorless to yellow liquid.

Registry Numbers and Inventories.
CAS
298-18-0
EC (EINECS/ELINCS)
206-060-6
RTECS
EJ8400000
RTECS class
Tumorigen; Mutagen
Beilstein/Gmelin
79831
Beilstein Reference
5-19-01-00185
Canada DSL/NDSL
DSL

Properties.
Formula
C4H6O2
Formula mass
86.10
Melting point, °C
3.9
Boiling point, °C
144
Vapor pressure, mmHg
8.5 (25 C)
Density
1.1835 g/cm3 (20 C)
Solubility in water
Very soluble
Refractive index
1.4425 (20 C)
Partition coefficient, pKow
0.20
Heat of vaporization
36.0 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.
Respirators
Wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter).
Small spills/leaks
If you should spill this chemical, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
No data.
Incompatibilities
Incompatible with acids, bases and oxidizing agents Reacts with 4-(4'-nitrobenzyl)pyridine Reacts with alcohols, amines, phenols.

Fire.
Flash Point,°C
45
Fire fighting
Fires involving this compound should be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
Fire potential
This chemical is combustible.

Health.
Exposure effects
   Ingestion
See inhalation.
   Inhalation
Exposure to this compound in humans may cause swollen eyelids, irritation of the upper respiratory tract and painful eye irritation 6 hours past exposure. Systemic toxicity may be caused by skin contact. It causes pronounced nasal and eye irritation at 10 ppm but barely recognizable at 5 ppm after 5-minute exposure. It may also cause mucous membrane irritation. Other symptoms include severe pulmonary irritation and depression of the hematopoietic system. Other symptoms include lacrimation, clouding of the cornea, labored breathing, lung congestion, atrophy of the thymus, involution of the spleen and decreased weight gain. Causes of death are pulmonary edema and shock following extreme local irritation. It may also cause reduced or loss of spermatogenesis, leukopenia and lymphopenia.
   Skin
See inhalation.
   Eyes
See inhalation

First aid
 
   Ingestion
If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. MMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.