DL-Epinephrine

  • (+/-)-Adrenaline
  • Benzyl alcohol, 3,4-dihydroxy-alpha-((methylamino)methyl)-, (+/-)
  • DL-Adrenaline
  • 1,2-Benzenediol, 4-(1-hydroxy-2-(methylamino)ethyl)-, (+/-)
  • (+/-)-Epinephrine
Formula
C9H13NO3
Structure
Description
Odorless light brown or nearly white crystals.
Uses
Medication.

Registry Numbers and Inventories.
CAS
329-65-7
EC (EINECS/ELINCS)
206-347-6
RTECS
DO2975000
RTECS class
Drug; Mutagen
Beilstein/Gmelin
2212160
Beilstein Reference
4-13-00-02927
Japan ENCS (MITI)
Listed

Properties.
Formula
C9H13NO3
Formula mass
183.20
Melting point, °C
211
Boiling point, °C
346
Critical temperature
529
Critical pressure
55.0
Partition coefficient, pKow
0.28

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter).
Small spills/leaks
If you spill this chemical, you should dampen the solid spill material with 5% acetic acid, then transfer the dampened material to a suitable container. Use absorbent paper dampened with 5% acetic acid to pick up any remaining material. Your contaminated clothing and the absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with 5% acetic acid followed by washing with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
No data.
Incompatibilities
Incompatible with heat, air, iron salts, and alkalis Incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides Incompatible with heat, air, iron salts, and alkalis.

Fire.
Fire fighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide, foam, or Halon extiguisher.

Health.
Exposure effects
   Ingestion
See inhalation.
   Inhalation
Pallor, tremor, anxiety, nervousness, rapid, forceful pulse, rise in blood pressure and temperature, rapid breathing, dilation of the pupils.
   Skin
See inhalation.
   Eyes
See inhalation

First aid
 
   Ingestion
If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. MMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.