DL-Ibotenic acid

  • alpha-Amino-2,3-dihydro-3-oxo-5-isoxazoleacetic acid
  • alpha-Amino-3-hydroxy-5-isoxazoleacetic acid hydrate
  • alpha-Amino-3-hydroxy-5-isoxazolessigsaure hydrate
  • Amino-(3-hydroxy-5-isoxazolyl)acetic acid
  • 5-Isoxazoleacetic acid, alpha-amino-2,3-dihydro-3-oxo
Formula
C5H6N2O4
Structure
Description
odorless colorless solid
Uses
Neurobiological tool.

Registry Numbers and Inventories.
CAS
2552-55-8
RTECS
NY2100000
RTECS class
Drug
Merck
12,4922
Beilstein/Gmelin
1075440

Properties.
Formula
C5H6N2O4
Formula mass
158.11
Decomposition point, °C
151 - 152
Solubility in water
Very soluble
pKa/pKb
1.59 (pKa)
Partition coefficient, pKow
0.13

Hazards and Protection.
Storage
Store in a tightly closed container. Deep freeze (below -20 C).
Handling
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Protection
Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.
Stability
No data.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen bromide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Health.
Exposure effects
   Ingestion
May cause irritation of the digestive tract. Poison by ingestion.
   Inhalation
May cause respiratory tract irritation. Toxic if inhaled.
   Skin
May cause skin irritation. Toxic in contact with skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Get medical aid immediately. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.