Dansyl chloride

  • 1-(Dimethylamino)-5-naphthalenesulfonyl chloride
  • 5-(Dimethylamino)-1-naphthalenesulfonyl chloride
  • 5-(N,N-Dimethylamino)-1-naphthalenesulfonyl chloride
  • 1-Naphthalenesulfonyl chloride, 5-(dimethylamino)
Formula
C12H12ClNO2S
Structure
Description
Yellow solid.
Uses
Substance is used in fluorescent labelling, column chromatography, HPLC.

Registry Numbers and Inventories.
CAS
605-65-2
EC (EINECS/ELINCS)
210-092-6
EC Class
corrosive
S 26 36/37/39 45
RTECS
QK3688000
RTECS class
Other
UN (DOT)
1759
Merck
13,2840
Beilstein/Gmelin
2217205
Beilstein Reference
4-14-00-02801
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C12H12ClNO2S
Formula mass
269.75
Melting point, °C
69.0 - 73.0
Solubility in water
Insoluble
pKa/pKb
11.62 (pKb)

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Disposal code
11
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, strong bases, moist air and water.
Decomposition
Hydrogen chloride, nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide.

Fire.
Fire fighting
Extinguish using agent most appropriate for surrounding fire.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
   Ingestion
May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns.
   Inhalation
May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema.
   Skin
May cause skin irritation and possible burns.
   Eyes
May cause eye irritation and possible burns.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1759
Response guide
Hazard class
8
Packing Group
I; II; III
 
HS Code
2921 49 80