Diacerein

  • 4,5-Diacetylrhein
  • 4,5-Diacetoxyanthraquinone-2-carboxylic acid
  • 1,8-Diacetoxy-3-carboxyanthraquinone
Formula
C19H12O8
Structure
Uses
Anti-osteoarthritic agent.

Registry Numbers and Inventories.
CAS
13739-02-1
EC (EINECS/ELINCS)
237-310-2
36/37/38
RTECS
CB8781000
RTECS class
Drug
Merck
12,3003
Beilstein/Gmelin
2184909
Beilstein Reference
3-10-00-04790

Properties.
Formula
C19H12O8
Formula mass
368.3
Boiling point, °C
632
Vapor pressure, mmHg
8E-17 (25 C)
Solubility in water
Very soluble
pKa/pKb
2.98 (pKa)
Heat of vaporization
98.2 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed. Store in a cool dry place.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide.

Fire.
Flash Point,°C
232
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
Irritant. Irritating to eyes, respiratory system and skin.
   Inhalation
Material is irritating to mucous membranes and upper respiratory tract.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water.
   Eyes
In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Transport.