Diazomethane

  • Azimethylene
  • Azomethylene
  • Diazirine
Formula
CH2=N+=N-
Structure
Description
Yellow gas with a musty odor.
Uses
Powerful methylating agent for acidic compound such as carboxylic acids, phenols, enols.

Registry Numbers and Inventories.
CAS
334-88-3
EC (EINECS/ELINCS)
206-382-7
EC Index Number
006-068-00-8
EC Class
Carcinogenic Category 2
RTECS
PA7000000
RTECS class
Tumorigen; Mutagen
Merck
12,3048
Beilstein/Gmelin
102415
Beilstein Reference
4-04-00-04430
Swiss Giftliste 1
G-1505

Properties.
Formula
CH2N2
Formula mass
42.04
Melting point, °C
-145
Boiling point, °C
-23
Vapor pressure, mmHg
>760
Vapor density (air=1)
1.45
Density
1.45 g/cm3 (20 C)
Solubility in water
Reacts

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Cold-insulating gloves. Face shield or eye protectin in combination with breathing protection.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
No data.
Incompatibilities
Strong oxidizing agents.

Fire.
Autoignition, °C
100 (explosion)
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Health
3

Health.
Exposure limit(s)
TLV: 0.2 ppm; 0.34 mg/m3 (ACGIH 1993-1994). OSHA PEL: TWA 0.2 ppm (0.4 mg/m3) NIOSH REL: TWA 0.2 ppm (0.4 mg/m3) NIOSH IDLH: 2 ppm
Carcinogin
G-A2
Poison_Class
1*
Exposure effects
The toxological properties of this substance have not been fully investigated.
   Inhalation
Symptoms: irritation eyes; cough, shortness breathing; headache, fatigue; flush skin, fever; chest pain, pulmonary edema, pneumonitis; asthma; liquid: frostbite Target Organs: Eyes, respiratory system.
   Skin
Redness, burning sensation, pain, serious frostbite. See inhalation.
   Eyes
Redness, pain. See inhalation.

First aid
 
   Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.
USCG CHRIS Code
DZM