Dibenz(c,h)acridine

  • 14-Azadibenz(a,j)anthracene
  • 1,2,7,8-Dibenzacridine
  • 3,4:5,6-Dibenzacridine
Formula
C21H13N
Structure
Description
Powder.
Uses
Used in biochemical research.

Registry Numbers and Inventories.
CAS
224-53-3
2 22 36/37
RTECS
HN1225000
RTECS class
Tumorigen; Mutagen
Beilstein/Gmelin
209259
Beilstein Reference
5-20-08-00656

Properties.
Formula
C21H13N
Formula mass
279.35
Melting point, °C
191
Boiling point, °C
534
Vapor pressure, mmHg
6E-11 (25 C)
Solubility in water
Insoluble
pKa/pKb
9.75 (pKb)
Heat of vaporization
78.0 kJ/mol

Hazards and Protection.
Storage
Maintain at 2-8 C. Keep container tightly closed. Keep away from heat sources.
Protection
Wear protective gloves, goggles and dustproof clothing.
Respirators
Dust mask with filter type P3.
Small spills/leaks
Stop dust cloud by covering with sand/earth. Solid spill: shovel. Carefully collect the spill/leftovers. Clean contaminated surfaces with an excess of water. Wash clothing and equipment after handling
Decomposition
Release of toxic and corrosive gases/vapours nitrous vapours, carbon monoxide - carbon dioxide upon thermal decomposition.

Fire.
Flash Point,°C
240
Fire fighting
Dilute toxic gases with water spray. Use compressed air/oxygen apparatus and a gas-tight suid.
Hazards
On burning: release of toxic and corrosive gases/vapours nitrous vapors, carbon monoxide and carbon dioxide

Health.
Exposure limit(s)
0.2 mg/m3 PEL
Carcinogin
I-2B, N-2, CP65
Exposure effects
   Ingestion
Irritation or burns of the esophagus or gastrointestinal tract are also possible if caustic or irritant chemicals are ingested.
   Inhalation
Causes irritation of the eyes, skin, and respiratory tract. In severe cases respiratory tract irritation can progress to ARDS/acute lung injury which may be delayed in onset for up to 24 to 72 hours in some cases.
   Skin
See Inhalation.
   Eyes
See Inhalation.

First aid
 
   Ingestion
Consider gastric lavage after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Administer charcoal as a slurry 240 mL water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents, 25 to 50 g in children (1 to 12 years), and 1 g/kg in infants less than 1 year old. Immediate dilution with milk or water may be of benefit in caustic or irritant chemical ingestions.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician may need to examine the area if irritation or pain persists.
   Eyes
Irrigate eye for at least 20 minutes with water or saline. If irritation persists, seek medical attention.

Transport.