Dibenzo(a,i)pyrene

  • BA 51-090462
  • DB(a,l)p
  • DB(a,i)p
  • Dibenzo(def,p)chrysene
  • Dibenzo(a,d)pyrene
  • 1,2:3,4-Dibenzopyrene
Formula
C24H14
Structure
Description
Yellow odorless crystals or flakes.
Uses
Experimental carcinogen.

Registry Numbers and Inventories.
CAS
191-30-0
EC (EINECS/ELINCS)
205-886-4
RTECS
HO6125000
RTECS class
Tumorigen; Mutagen
UN (DOT)
1325
Beilstein/Gmelin
2054068
Beilstein Reference
4-05-00-02803
Swiss Giftliste 1
G-1776

Properties.
Formula
C24H14
Formula mass
302.38
Melting point, °C
232
Boiling point, °C
514
Solubility in water
Insoluble
Partition coefficient, pKow
7.71

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Make no contact with the spilled material. ELIMINATE all ignition sources and ground all equipment. With clean shovel place material into clean, dry container and cover loosely; move containers from spill area.
Stability
No data.
Incompatibilities
Can react exothermically with bases and with diazo compounds.

Fire.
Fire fighting
Small Fires: Dry chemical, carbon dioxide, sand, earth, water spray or regular foam. Large Fires: Water spray, fog or regular foam.
Fire potential
Flammable/combustible material. May be ignited by friction, heat, sparks or flames.
Combustion products
Fire may produce irritating and/or toxic gases.

Health.
Exposure limit(s)
OSHA: Permissible Exposure Limit: Table Z-1 8 hr Time Weighted Avg: 0.2 mg/m3.
Carcinogin
I-2B, N-2, CP65
Poison_Class
1*
Exposure effects
In experimental animal studies, PAHs and metabolites cross the placenta. Female offspring of experimental animals exposed to PAHs during pregnancy have a decrease in the number of functional oocytes, sometimes such that they are infertile. <br>PAHs are lipophilic and are excreted in breast milk, allowing for secondary exposure of nursing infants, although the potential significance of such exposure has not been determined.
   Ingestion
Leukoplakia and cancers of the lip and oral cavity can develop with chronic exposure.
   Inhalation
Irritation, chronic cough, bronchitis, and bronchogenic cancer can occur with chronic exposure.
   Skin
Coal tar warts (precancerous lesions enhanced by uv light exposure), erythema, dermal burns, acneiform lesions, photosensitization and cancer may develop following chronic exposure.
   Eyes
See Skin.

First aid
 
   Ingestion
Toxicity from these substances involves chronic exposure, toxicity after acute ingestions is unlikely and gastric decontamination is generally not indicated.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
1325
Response guide
Hazard class
4.1
Packing Group
II; III
 
32. Aromatic hydrocarbons