Dichloroethyl ether

  • Di(2-chloroethyl ether
  • 1,1'-Oxybis[2-chloroethane]
  • bis(2-Chlorethyl)ether
  • sym-Dichloroethyl ether
Formula
(ClCH2CH2)2O
Structure
Description
Colorless liquid with a chlorinated solvent-like odor.
Uses
Reagent for organic synthesis, solvent.

Registry Numbers and Inventories.
CAS
111-44-4
EC (EINECS/ELINCS)
203-870-1
EC Index Number
603-029-00-2
EC Class
Flammable; Very toxic; Harmful
R 10 26/27/28 68
S 7/9 27 38 45
RTECS
KN0875000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Primary Irritant
UN (DOT)
1916
Merck
13,3091
Beilstein/Gmelin
605317
Beilstein Reference
4-01-00-01375
RCRA
U025
EPA OPP
29501
Swiss Giftliste 1
G-1520
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C4H8Cl2O
Formula mass
143.01
Melting point, °C
-44
Boiling point, °C
178
Vapor pressure, mmHg
2 (30 C)
Vapor density (air=1)
4.93
Saturation Concentration
921 ppm (0.09%) at 20 C (calculated)
Odor Threshold Odor threshold 90 mg/m3
Critical temperature
429
Critical pressure
32.2
Density
1.22917 g/cm3 (12 C)
Solubility in water
10 g/L
Viscosity
2.37 cp (20 C)
Surface tension
37.9 g/s2 @ 19 C
Refractive index
1.4548 (20 C)
Dipole moment
2.47 D
Dielectric constant
20.5 (20 C)
Partition coefficient, pKow
1.29
Heat of fusion
8.7 kJ/mol
Heat of vaporization
38.38 kJ/mol
Heat of combustion
-17470 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
B3 D1A D2B
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Remove all sources of ignition. Use a spark-proof tool. A vapor suppressing foam may be used to reduce vapors.
Disposal code
9
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, coatings, plastics, rubber.
Decomposition
Hydrogen chloride, carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
55
Autoignition, °C
365
Lower exp. limit, %
2.7
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
Fire potential
Moderately flammable. Combustion with moderate heating.
Hazards
May form phosgene or hydrogen chloride in fires. There is danger of explosion when ethers are heated or exposed to flames or sparks. Ethers tend to form peroxides; when ethers containing peroxides are heated, they can detonate. May be ignited by heat, sparks, or flames. Container may explode in heat of fire. Vapor explosion and poison hazard indoors, outdoors or in sewers. Decomposes in the presence of moisture to form hydrochloric acid. Emits toxic fumes when heated to decomposition. Reacts vigorously with oleum and chlorosulfonic acid. Ethers tend to form peroxides upon standing. Heating peroxide-containing ethers can cause detonation.
Combustion products
May form phosgene or hydrogen chloride in fires.
Health
2
 
Flammability
2
 
 
Reactivity
1
 

Health.
Exposure limit(s)
NIOSH REL: Ca TWA 5 ppm (30 mg/m3) ST 10 ppm (60 mg/m3) [skin] See Appendix A OSHA PEL: TWA 15 ppm (90 mg/m3) [skin] IDLH Ca [100 ppm]
Carcinogin
CP65
Poison_Class
2
Exposure effects
Potential cancer hazard.
   Ingestion
Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. Ingestion of large amounts may cause CNS depression.
   Inhalation
May be fatal if inhaled. Causes respiratory tract irritation. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. May cause burning sensation in the chest.
   Skin
Causes skin irritation. May be fatal if absorbed through the skin. May cause irritation and dermatitis. May cause cyanosis of the extremities.
   Eyes
Causes severe eye irritation. Lachrymator. May cause chemical conjunctivitis and corneal damage.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1916
Response guide
Hazard class
6.1
Packing Group
II
 
USCG CHRIS Code
DEE
 
HS Code
2909 19 00
 
Std. Transport #
4921550
 
IMO Chemical Code
17
IMO Pollution Category
B
IMO Hazard code
S/P