Diethyl chlorophosphonate

  • Diethoxyphosphoryl chloride
  • Ethyl phosphorochloridate
  • Chlorodiethoxyphosphine oxide
  • Phosphorochloridic acid, diethyl ester
  • O,O-Diethyl chlorophosphate
  • Phosphoric acid chloride diethyl ester
Formula
C4H10ClO3P
Structure
Description
Clear liquid.
Uses
Intermediate in organic synthesis.

Registry Numbers and Inventories.
CAS
814-49-3
EC (EINECS/ELINCS)
212-396-4
RTECS
TD1400000
RTECS class
Primary Irritant
UN (DOT)
2927
Beilstein/Gmelin
471433
Beilstein Reference
4-01-00-01345
Canada DSL/NDSL
NDSL
US TSCA
Listed
New Zealand
Listed

Properties.
Formula
C4H10ClO3P
Formula mass
172.54
Boiling point, °C
81
Vapor density (air=1)
5.94
Density
1.205 g/cm3 (19 C)
Solubility in water
Slightly soluble
Surface tension
32 g/s2 (20 C)
Refractive index
1.419 (20 C)

Hazards and Protection.
Storage
Store in a cool, dry place. Keep container closed when not in use.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Discard contaminated shoes.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Decomposition
Irritating and toxic fumes and gases, chloride fumes, phosphorous fumes.

Fire.
Flash Point,°C
61
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use agent most appropriate to extinguish fire. Cool containers with flooding quantities of water until well after fire is out. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
Combustible
Hazards
Emits very toxic fumes of chloride and phosphorus oxides when heated to decomposition.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
Fever, low heart rate and abnormally low blood pressure, or rapid heart rate and elevated blood pressure may occur. Headache, dizziness, muscle spasms and profound weakness are common. Alterations of level of consciousness, anxiety, paralysis, seizures and coma may occur. Seizures may be more common in children.
   Ingestion
May be fatal if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
May cause respiratory tract irritation. Aspiration may cause respiratory swelling and pneumonitis.
   Skin
May cause skin irritation. May be fatal if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Induce vomiting only when instructed to do so by a physician.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2927
Response guide
Hazard class
6.1
Packing Group
I; II
 
USCG CHRIS Code
DEY