Diethyl malonate

  • Ethyl malonate
  • Carbethoxyacetic ester
  • Dicarbethoxymethane
  • Diethyl propanedioate
Formula
C2H5OOCCH2COOC2H5
Structure
Description
Clear, colorless liquid with a fruity odor.
Uses
Production of barbiturates.

Registry Numbers and Inventories.
CAS
105-53-3
EC (EINECS/ELINCS)
203-305-9
RTECS
OO0700000
RTECS class
Primary Irritant
Merck
13,3856
Beilstein/Gmelin
774687
Beilstein Reference
4-02-00-01881
Swiss Giftliste 1
G-3223
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C7H12O4
Formula mass
160.17
Melting point, °C
-50
Boiling point, °C
199
Vapor pressure, mmHg
1 (42 C)
Vapor density (air=1)
5.52
Density
1.07607 g/cm3 (0 C)
Solubility in water
Slightly soluble
Viscosity
1.88 cp (25 C)
Surface tension
35.5 g/s2 (-190.9 C)
Refractive index
1.4143 (20 C)
Heat of vaporization
42.71 kJ/mol
Heat of combustion
-3603 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Keep container closed when not in use.
Handling
Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Scoop up with a nonsparking tool, then place into a suitable container for disposal. Remove all sources of ignition. Provide ventilation. Clean up residual material by washing area with a 2-5% solution of soda ash.
Disposal code
1
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Acids, bases, oxidizing agents, and reducing agents.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
93
Upper exp. limit, %
7.3
Lower exp. limit, %
1.3
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Cool containers with flooding quantities of water until well after fire is out.
Health
1
 
Flammability
2
 
 
Reactivity
0
 

Health.
Poison_Class
4
Exposure effects
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause central nervous system effects.
   Inhalation
May cause respiratory tract irritation. May cause narcotic effects in high concentration.
   Skin
May cause skin irritation. Prolonged and/or repeated contact may cause irritation and/or dermatitis.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
   Skin
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
HS Code
2917 19 10