- Sulfuric acid, diethyl ester
Colorless, oily liquid, darkens with age, faint ethereal or peppermint odor.
Ethylating agent, as an accelerator in sulfation of ethylene, in some sulfonations.
Registry Numbers and Inventories.
EC Index Number
Carcinogenic Category 2; Mutagenic Category 2; Harmful; Corrosive
R 45 46 20/21/22 34
S 53 45
Tumorigen; Mutagen; Reproductive Effector; Primary Irritant
Swiss Giftliste 1
Japan ENCS (MITI)
Melting point, °C
Boiling point, °C
Vapor pressure, mmHg
0.32 (25 C)
Vapor density (air=1)
250 ppm (0.02%) at 20 C (calculated)
1.179 g/cm3 (20 C)
Solubility in water
1.79 cp @ 20C
34.61 g/s2 (13 C)
1.40037 (20 C)
4.41 D (25 C)
16.2 (20 C)
Partition coefficient, pKow
Heat of vaporization
Hazards and Protection.
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.
Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Do not allow contact with water. Discard contaminated shoes. Keep from contact with moist air and steam.
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation. Do not get water inside containers.
Stable under normal temperatures and pressures. Decomposes when heated.
Moisture, potassium-tert-butoxide, iron + water, alkalies, nitric acid, aluminum, peroxides, strong bases, strong oxidizing agents, 2,7-dinitro-9-phenylphenanthridine + water.
Carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide.
Upper exp. limit, %
Lower exp. limit, %
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Water or foam may cause frothing. Use water spray to cool fire-exposed containers. Do NOT get water inside containers.
Combustible material: may burn but does not ignite readily.
Containers may explode when heated.
Highly toxic fumes contaning sulfur oxides may be generated along with thermal decomposition products such as ethyl ether and ethylene.
I-2A, N-2, CP65
May cause fetal effects. May cause cancer in humans. Effects may be delayed. Chronic exposure may cause lung damage. Laboratory experiments have resulted in mutagenic effects. Prolonged exposure may cause corneal erosion, conjunctivitis, and possible blindness.
May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. May cause perforation of the digestive tract. May be harmful if swallowed. May cause systemic effects.
Causes chemical burns to the respiratory tract. Aspiration may lead to pulmonary edema. May be harmful if inhaled. May cause systemic effects.
Harmful if absorbed through the skin. Causes skin burns. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
Causes eye burns.
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).