Diethylarsine

  • Diethylarsenic hydride
Formula
C4H11As
Structure
Description
Liquid.
Uses
Medication.

Registry Numbers and Inventories.
CAS
692-42-2
Beilstein/Gmelin
1730910
Beilstein Reference
3-04-00-01797
RCRA
P038
Swiss Giftliste 1
G-5502

Properties.
Formula
C4H11As
Formula mass
134.05
Boiling point, °C
105
Vapor pressure, mmHg
23.4 (7.9 C)
Density
1.1338 g/cm3
Refractive index
1.4709 (20 C)
Heat of vaporization
34.2 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate clothing to prevent any reasonable probability of skin contact. Wear eye protection to prevent any possibility of eye contact.
Respirators
At concentrations above the NIOSH rel, or where there is no rel, at any detectable concentration. Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive pressure-mode. Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive-pressure mode.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
No data.
Incompatibilities
Strong oxidizing agents.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Fire potential
This material is spontaneously flammable in air.

Health.
Exposure limit(s)
IDHL: NIOSH considers arsine to be a potential occupational carcinogen.
Poison_Class
1
Exposure effects
Abnormally low blood pressure and rapid heart rate are common early signs. Fever and rapid breathing may occur. Elevated blood pressure has been associated with chronic environmental arsenic exposure. Altered mental status, seizures, toxic delirium, encephalopathy, and delayed peripheral neuropathy are complications of acute arsenic poisoning. Inorganic arsenic crosses the placenta and may result in spontaneous abortion or stillbirth with either acute or chronic poisoning.
   Ingestion
Acute toxicity results in early symptoms of abdominal pain, severe vomiting and diarrhea, as well as dryness of the oral and nasal cavities.
   Inhalation
Respiratory tract irritation may occur. Cardiogenic or noncardiogenic pulmonary edema and respiratory failure may develop in severe poisonings.
   Skin
Skin findings may include hyperpigmentation, keratoses, and epidermoid carcinomas. Mee's lines of the nails are common. Trivalent arsenic compounds are corrosive to the skin. Arsenic trioxide and pentoxide are sensitizers.
   Eyes
As(III) is corrosive to the eyes, mouth, and mucous membranes. Perforation of the nasal septum can occur.

First aid
 
   Ingestion
Gastric decontamination - aggressive decontamination with gastric lavage is recommended. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
USCG CHRIS Code
DEI