Diethylstilbestrol

  • Stilboestrol
  • (E)-alpha,beta-Diethylstilbene-4,4'-diol
Formula
C18H20O2
Structure
Description
Odorless tasteless white crystalline powder.
Uses
Therap cat: estrogen.

Registry Numbers and Inventories.
CAS
56-53-1
EC (EINECS/ELINCS)
200-278-5
RTECS
WJ5600000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Hormone; Natural Product
Merck
12,3177
Beilstein/Gmelin
2056095
Beilstein Reference
4-06-00-06856
RCRA
U089
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C18H20O2
Formula mass
268.36
Melting point, °C
169-172
Boiling point, °C
407
Solubility in water
Insoluble
Refractive index
1.5299
Partition coefficient, pKow
5.07

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions.
Stability
No data.
Incompatibilities
Strong oxidizing agents, strong bases, acids, chlorides, acid anhydrides.
Decomposition
Carbon monoxide, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.
Fire potential
This material is probably combustible.

Health.
Carcinogin
I-1, N-1, CP65
Exposure effects
May cause liver and kidney damage.
   Ingestion
May cause irritation of the digestive tract. Ingestion causes human reproductive effects.
   Inhalation
Inhalation of dust may cause respiratory tract irritation.
   Skin
May cause skin irritation. Causes glandular system effects by skin contact.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
USCG CHRIS Code
DSB