(+)-Digitoxigenin

  • 3,14,21-Trihydroxy-20(22)-norcholenic acid lactone
  • 5b,20(22)-Cardenolide-3b,14-diol
Formula
C23H34O4
Structure
Description
Digitalis is a natural product that comes from the purple foxglove plant, or in botany it is known as Digitalis purpurea.
Uses
Medication that blocks the sodium-potassium pump.  The result of this is the increase in calcium, which increases the heart muscle action.

Registry Numbers and Inventories.
CAS
143-62-4
EC (EINECS/ELINCS)
205-603-4
RTECS
FH4975000
RTECS class
Drug
UN (DOT)
2811
Merck
12,3205
Beilstein/Gmelin
95448
Beilstein Reference
5-18-03-00348

Properties.
Formula
C23H34O4
Formula mass
374.52
Melting point, °C
253 - 255
Boiling point, °C
549
Vapor pressure, mmHg
2E-14 (25 C)
Solubility in water
Insoluble
Heat of vaporization
95.3 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, Strong acids.
Decomposition
Carbon monoxide, Carbon dioxide.

Fire.
Flash Point,°C
188
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Emits toxic fumes under fire conditions.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Toxic if swallowed. Target organ(s): Heart.
   Ingestion
Toxic if swallowed.
   Inhalation
Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.
   Skin
May cause skin irritation. May be harmful if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
II