Diglycidyl ether

  • DGE
  • Di(epoxypropyl)ether
  • Bis(2,3-epoxypropyl)ether
  • 2,2'-[Oxybis(methylene)]bisoxirane
Formula
C6H10O3
Structure
Description
Colorless liquid. Strong, irritating odor.
Uses
Reactive diluent for epoxy resins, chemical intermediate, stabilizer of chlorinated organic compound, textile-treating agent.

Registry Numbers and Inventories.
CAS
2238-07-5
EC (EINECS/ELINCS)
218-802-6
RTECS
KN2350000
RTECS class
Tumorigen; Mutagen; Primary Irritant
Beilstein/Gmelin
105358
Beilstein Reference
5-17-03-00046
Swiss Giftliste 1
G-1544
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C6H10O3
Formula mass
130.16
Boiling point, °C
260
Vapor pressure, mmHg
0.09
Vapor density (air=1)
3.78
Odor Threshold Odor threshold 25 mg/m3
Density
1.119 g/cm3 (23 C)
Solubility in water
Soluble
Refractive index
1.4499 (20 C)

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate clothing to prevent any reasonable probability of skin contact. Wear eye protection to prevent any possibility of eye contact.
Respirators
Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode. Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive-pressure mode.
Small spills/leaks
(Non-Specific -- Poison, Flammable Liquid, n.o.s.) Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Wear positive pressure breathing apparatus and special protective clothing. Shut off ignition sources; no flares, smoking, or flames in hazard area. Do not touch spilled material; stop leak if you can do so without risk. Use water spray to reduce vapors. Small spills: absorb with sand or other noncombustible absorbent material and place into containers for later disposal. Large spills: dike far ahead of spill for later disposal.
Stability
No data.
Incompatibilities
React with acids, bases, and oxidizing and reducing agents.

Fire.
Flash Point,°C
64
Fire fighting
(Non-Specific -- Poison, Flammable Liquid, n.o.s.) Move container from fire area if you can do so without risk. Cool containers that are exposed to flames with water from the side until well after fire is out. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material. Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Wear positive pressure breathing apparatus and special protective clothing.(Non-Specific -- Poison, Flammable Liquid, n.o.s.) Small fires: dry chemical, carbon dioxide, water spray, or foam. Large fires: water spray, fog, or foam.
Hazards
May be ignited by heat, sparks, or flames. Container may explode in heat of fire. Vapor explosion and poison hazard indoors, outdoors or in sewers. Avoid strong oxidizers.

Health.
Exposure limit(s)
TLV: 0.1 ppm; 0.53 mg/m3 (as TWA) (ACGIH 1997). OSHA PEL: C 0.5 ppm (2.8 mg/m3) NIOSH REL: Ca TWA 0.1 ppm (0.5 mg/m3) See Appendix A NIOSH IDLH: Potential occupational carcinogen 10 ppm
Poison_Class
2
Exposure effects
Ataxia and coma have been observed in exposed experimental animals. Decreased spermatogenesis or focal testicular necrosis have been observed in animals.
   Ingestion
Gastrointestinal tract irritation may be predicted based on the other irritant properties of diglycidyl ether.
   Inhalation
Inhalation exposure causes irritation of the respiratory tract. Pulmonary edema might occur.
   Skin
Dermal irritation and sensitization may be seen.
   Eyes
Severe corneal irritation may be seen. Mucosal irritation of the nose and throat may be seen.

First aid
 
   Ingestion
The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Treat dermal irritation or burns with standard topical therapy. Treatment should include recommendations listed in the oral exposure section when appropriate.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.