Diisobutyl ketone

  • 2,6-Dimethyl-4-heptanone
  • Isovalerone
  • Valerone
  • 2,6-Dimethylheptan-4-one
Formula
(CH3)2CHCH2COCH2CH(CH3)2
Structure
Description
Colorless liquid with a mild peppermint odor.
Uses
Solvent for nitrocellulose, for milled crepe rubber, vinylite, synthetic coatings and as a dispersant for organosol type resins, intermediate in synthesis of inhibitors, pharmaceuticals, dyes, & insecticides.

Registry Numbers and Inventories.
CAS
108-83-8
EC (EINECS/ELINCS)
203-620-1
EC Index Number
606-005-00-X
EC Class
Flammable; Irritant
R 10 37
RTECS
MJ5775000
RTECS class
Human Data; Primary Irritant
UN (DOT)
1157
Beilstein/Gmelin
1743163
Beilstein Reference
4-01-00-03360
EPA OPP
44107
Swiss Giftliste 1
G-1546
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C9H18O
Formula mass
142.24
Melting point, °C
-46
Boiling point, °C
165
Vapor pressure, mmHg
1.7 (20 C)
Vapor density (air=1)
4.9
Saturation Concentration
9.3 g/m3 at 20 C
Evaporization number
0.2 (butyl acetate = 1)
Odor Threshold Odor threshold < 0.11 ppm
Critical temperature
346
Critical pressure
29.03
Density
0.806 g/cm3 (20 C)
Solubility in water
500 mg/L
Viscosity
1.32 cp (0 C)
Surface tension
23.92 g/s2 (22 C)
Refractive index
1.4101 (20 C)
Heat of vaporization
37.0 kJ/mol
Heat of combustion
-5300 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
B3
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Disposal code
1
Stability
Stable under normal temperatures and pressures. However, forms peroxides of unknown stability.
Incompatibilities
Strong oxidizers. May attack some forms of plastic, rubber and coatings.
Decomposition
Carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
49
Autoignition, °C
396
Upper exp. limit, %
7.1
Lower exp. limit, %
0.8
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: Use water spray to cool fire-exposed containers. Water may be ineffective. In case of fire, use water fog, dry chemical, carbon dioxide, or regular foam. Use agent most appropriate to extinguish fire. Do NOT use straight streams of water.
Fire potential
HIGHLY FLAMMABLE.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. May polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
2
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV: 25 ppm; 145 mg/m3 (as TWA) (ACGIH 1997). OSHA PEL: TWA 50 ppm (290 mg/m3) NIOSH REL: TWA 25 ppm (150 mg/m3) NIOSH IDLH: 500 ppm
Poison_Class
4
Exposure effects
Chronic exposure may cause skin effects. May cause liver and kidney effects based upon studies with laboratory animals.
   Ingestion
Causes irritation to the gastrointestinal tract. Symptoms may include nausea, vomiting and diarrhea.
   Inhalation
Inhalation of vapors irritates the respiratory tract. May cause coughing, dizziness, dullness, nausea, vomiting and headache. Higher concentrations can produce central nervous system depression, narcosis, and unconsciousness. The odor of this material is recognized at levels well below those which cause adverse effects and should be sufficient warning against overexposure.
   Skin
May cause irritation with redness and pain.
   Eyes
Liquid and vapor causes irritation, redness, and pain.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1157
Response guide
Hazard class
3
Packing Group
III
 
USCG CHRIS Code
DIK
 
HS Code
2914 19 90
 
Std. Transport #
4912040
 
IMO Chemical Code
18
IMO Pollution Category
D