Diisopropylamine

  • N-(1-Methylethyl)-2-propanamine
  • Bis(isopropyl)amine
  • DIPA
Formula
(CH3)2CHNHCH(CH3)2
Structure
Description
Colorless liquid with a fishy, ammonia-like odor.
Uses
Catalyst, synthetic intermediate.

Registry Numbers and Inventories.
CAS
108-18-9
EC (EINECS/ELINCS)
203-558-5
EC Index Number
612-129-00-5
EC Class
Highly flammable; Harmful; Corrosive
R 11 20/22 34
S 16 26 36/37/39 45
RTECS
IM4025000
RTECS class
Mutagen
UN (DOT)
1158
Merck
13,3219
Beilstein/Gmelin
605284
Beilstein Reference
4-04-00-00510
Swiss Giftliste 1
G-1549
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H15N
Formula mass
101.19
Melting point, °C
-61
Boiling point, °C
84
Vapor pressure, mmHg
74 (25 C)
Vapor density (air=1)
3.5
Saturation Concentration
6.6% at 20 C
Odor Threshold Odor threshold 1.8 ppm
Critical temperature
249.0
Critical pressure
29.8
Density
0.717 g/cm3 (20 C)
Solubility in water
Miscible
Viscosity
0.40 cp @ 25C
Surface tension
19.64 g/s2 @ 20 C
Refractive index
1.3924 (20C)
Dielectric constant
3.04
pKa/pKb
3.24 (pKb)
Partition coefficient, pKow
1.40
Heat of vaporization
30.4 kJ/mol
Heat of combustion
-136.3 kJ/mol

Hazards and Protection.
Storage
Protect against physical damage. Store in a cool, dry well-ventilated location, away from any area where the fire hazard may be acute. Outside or detached storage is preferred. Separate from incompatibles. Containers should be bonded and grounded for transfers to avoid static sparks. Storage and use areas should be No Smoking areas
B2 D1A E
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Use a full facepiece respirator with organic vapor cartridge may be worn up to 50 times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Remove all sources of ignition. A vapor suppressing foam may be used to reduce vapors.
Disposal code
5
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Acids, oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
-17
Autoignition, °C
295
Upper exp. limit, %
8.5
Lower exp. limit, %
1.5
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Do NOT get water inside containers. For large fires, use water spray, fog or alcohol-resistant foam.
Fire potential
Extremely flammable liquid.
Hazards
Vapors are heavier than air and may travel to a source of ignition and flash back. Containers may explode in the heat of a fire.
Combustion products
Toxic oxides of nitrogen may form in fires.
Health
3
 
Flammability
3
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV: 5 ppm; 21 mg/m3 (skin) (ACGIH 1996). OSHA PEL: TWA 5 ppm (20 mg/m3) skin NIOSH REL: TWA 5 ppm (20 mg/m3) skin NIOSH IDLH: 200 ppm
Poison_Class
3
Exposure effects
Chronic inhalation may cause lung problems. Prolonged or repeated skin exposure may cause dermatitis.
   Ingestion
Harmful if swallowed. Symptoms may parallel those from inhalation. Corrosive. Swallowing can cause severe burns of the mouth, throat, and stomach. Can cause sore throat, vomiting, diarrhea.
   Inhalation
Respiratory irritant. Vapors irritate the nose, throat, and respiratory tract. Other symptoms may include headache, vision problems, and nausea. High concentrations can cause pulmonary edema.
   Skin
Prolonged and/or repeated contact may cause irritation and/or dermatitis. Causes severe skin irritation and burns.
   Eyes
Exposure to concentrations between 25 and 50 ppm may cause disturbances of vision described as haziness. Causes severe eye irritation and possible burns. May cause temporary visual impairment.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed.

Transport.
UN number
1158
Response guide
Hazard class
3
Packing Group
II
 
USCG CHRIS Code
DIA
 
7 Aliphatic amines
HS Code
2921 19 80
 
Std. Transport #
4909148
 
IMO Chemical Code
17
IMO Pollution Category
C
IMO Hazard code
S/P