Dimethicone

  • DC-1664
  • Dimethicone-350
  • Dimeticone
  • Dow-Corning-1664
  • Mirasil-DM-20
  • Viscasil-5M
Formula
Unspecified
Uses
Ointment base and topical drug ingredient skin protectant.

Registry Numbers and Inventories.
CAS
9006-65-9
RTECS
IP6562500
RTECS class
Other
Beilstein/Gmelin
NA
Austrailia AICS
Listed
New Zealand
Listed

Properties.

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
No data.
Incompatibilities
Strong oxidizing agents.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Exposure effects
The toxological properties of this substance have not been fully investigated.
   Inhalation
Silicone injection has been associated with the development of fatal pulmonary edema, pneumonitis, pleural effusion, ards and dyspnea.
   Skin
Hypopigmentation and peau d'orange skin changes have been reported after silicone injection or implantation.

First aid
 
   Ingestion
Significant toxicity is not anticipated after ingestion. Treatment is symptomatic and supportive. Consider activated charcoal only after very large ingestions. The target organs for migrating silicones have been chiefly the liver and lungs. In most cases, aggressive supportive care has been adequate to handle the immediate problem. No specific antidotes exist. No treatment is necessary for oral ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Inhalation hazard is low due to the low vapor pressure of most silicone fluids. Treatment is symptomatic and supportive.
   Skin
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.