Dimethyl chlorothiophosphate

  • Dimethyl thiophosphoryl chloride
  • Dimethyl chlorothiophosphate
  • O,O-dimethyl phosphorochloridothioate
Formula
C2H6ClO2PS
Structure
Description
Colorless to light amber liquid with a stench.
Uses
Intermediate for insecticides, pesticides, fungicides, oil & gasoline additives, plasticizers, corrosion inhibitors, flame retardants, flotation agents.

Registry Numbers and Inventories.
CAS
2524-03-0
EC (EINECS/ELINCS)
219-754-9
RTECS
TD1830000
RTECS class
Mutagen
UN (DOT)
2267
Beilstein/Gmelin
471300
Beilstein Reference
4-01-00-01263
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C2H6ClO2PS
Formula mass
160.56
Boiling point, °C
66
Vapor pressure, mmHg
4
Vapor density (air=1)
5.54
Density
1.3414 g/cm3 (0 C)
Solubility in water
Decomposes
Refractive index
1.4776

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Store protected from moisture.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Use and store under nitrogen. Do not allow contact with water. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Keep from contact with moist air and steam.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Do not get water inside containers. Cover with dry earth, dry sand, or other non-combustible material followed with plastic sheet to minimize spreading and contact with water.
Stability
Stable under normal temperatures and pressures. Begins autocatalytic decomposition at temperatures above 120 C.
Incompatibilities
Moisture, water, strong bases, strong oxidizing agents.
Decomposition
Hydrogen chloride, phosphine, carbon monoxide, oxides of sulfur, oxides of phosphorus, carbon dioxide, chloride fumes.

Fire.
Flash Point,°C
105
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Combustible Liquid. Containers may explode when heated. Water hydrolyzes material liberating acidic gas which in contact with metal surfaces can generate flammable and/or explosive hydrogen gas. Extinguishing media: Do NOT use water directly on fire. Use water spray to cool fire-exposed containers. Use foam, dry chemical, or carbon dioxide. Do NOT get water inside containers.
Fire potential
This material may burn but does not ignite readily.
Hazards
This material may ignite combustibles (wood, paper, oil, etc.). When heated it emits very toxic fumes of chlorine containing compounds, phosphorus oxides, and sulfur oxides.
Combustion products
When heated to decomp, can emit highly toxic fumes of oxides of phosphorous.
Health
3
 
Flammability
2
 
 
Reactivity
2
 

Health.
Exposure effects
Headache, dizziness, muscle spasms, and profound weakness are common. Alterations of level of consciousness, eeg changes, seizures and coma may occur. Seizures may be more common in children. Peripheral neuropathy of the mixed sensory-motor type may be delayed in onset by 6 to 21 days. Recovery may be slow or incomplete.<br>Most of the organophosphates have not been teratogenic in experimental animals, but some have caused lower fetal or birth weights and/or higher neonatal mortality.<br>Sporadic reports of human birth defects related to organophosphates have not been verified.
   Ingestion
Causes gastrointestinal tract burns. May cause liver damage. May cause perforation of the digestive tract. May be harmful if swallowed. Ingestion of large amounts may cause CNS depression. May cause excessive salivation, abdominal pain, incontinence, muscle cramps and weakness, and confusion.
   Inhalation
May be fatal if inhaled. Causes chemical burns to the respiratory tract. May cause effects similar to those described for ingestion. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. May cause systemic effects. May cause burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting. Inhalation at high concentrations may cause CNS depression and asphixiation.
   Skin
Harmful if absorbed through the skin. Causes skin burns. If absorbed, may cause central nervous system effects. May cause cyanosis of the extremities. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
   Eyes
Causes eye burns. May cause conjunctivitis and corneal inflammation. Causes lachyrmation (tearing), blurred vision, and may cause temporar y lesions.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth respiration if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
2267
Response guide
Hazard class
6.1
Packing Group
II
 
USCG CHRIS Code
DHI